Anhang Forschung/ Wissenschaftliche Tätigkeiten 1. Publikationen 28 Medline/ ISI- gelistete Publikationen 13 x Erstautor Kumulativer gewichteter IF: 26.12 1. Haisch A, Groger A, Radke C, Ebmeyer J, Sudhoff H, Grasnick G, Jahnke V, Burmester GR, Sittinger M. Protection of autogenous cartilage transplants from resorption using membrane encapsulation. HNO. 2000 Feb;48(2):119-24 2. Haisch A, Groger A, Radke C, Ebmeyer J, Sudhoff H, Grasnick G, Jahnke V, Burmester GR, Sittinger M. Macroencapsulation of human cartilage implants: pilot study with polyelectrolyte complex membrane encapsulation. Biomaterials. 2000 Aug;21(15):1561-6 3. Haisch A, Kläring S, Groger A, Gebert C, Sittinger M. A tissue engineering model for auricular shaped cartilage implant manufacturing. Eur Arch Otorhinolaryngol. 2002 259: 316–321 4. Groger A, Kläring S, Merten, HA, Holste J, Kaps C, Sittinger M. Preliminary study: Tissue engineering of periosteum for mandible augmentation in the immunocompetent minipig. Scand J Plast Reconstr Surg Hand Surg. 2003; 37(3):129-33. 5 .Groger A, Aslani A, Wolter T, Noah EM, Pallua N. A rare case of Cannabis- Arteritis. Vasa 2003 May;32(2):95-7. 6. Haisch A, Wanjura F Radke C, Leder-Jöhrens K, Groger A , Endres M, Klaering S, Loch A, Sittinger M. Immunomodulation of tissue-engineered transplants: in vivo bone generation from methylprednisolone-stimulated chondrocytes. Eur Arch Otorhinolaryngol. 2004 Apr;261(4):216-24. 7. Groger A, Ulrich D, Unglaub F, Pallua N. Varicella-associated necrotizing fasciitis in a child. Unfallchirurg. 2004 Apr;107(4):325-7. 8. Haisch A, Groger A, Gebert C, Leder K, Ebmeyer J, Sudhoff H, Jovanovic S, Sedlmaier B, Sittinger M. Creating artificial perichondrium by polymer complex membrane macroencapsulation: immune protection and stabilization of subcutaneously transplanted tissue-engineered cartilage. Eur Arch Otorhinolaryngol. 2005 Apr;262(4):338-44. 9. Haisch A, Duda GN, Schroeder D, Groger A, Gebert C, Leder K, Sittinger M. Morphology and biomechanical characteristics of subcutaneously implanted tissue engineered human septal cartilage. Eur Arch Otorhinolaryngol. 2005 Dec;262(12):993-7. 10. Unglaub F, Guehring T, Fuchs PC, Perez-Bouza A, Groger A, Pallua N. Necrotizing fasciitis following therapeutic injection in a shoulder joint. Orthopade. 2005 Mar;34(3):250-2. 11. Yagmur E, Piatkowski A, Groger A, Pallua N, Gressner AM, Kiefer P. Bleeding complication under Gingko biloba medication. Am J Hematol. 2005 Aug;79(4):343-4. 12. Groger A, Bozkurt A, Franke E, Hornchen H, Steinau G, Piatkowski A, Fuchs P, Pallua N. Ischaemic necrosis of small and large intestine in a 2-year-old child with 20% partial thickness burns: a case report. Burns 2005 Nov;31(7):930-2. 13. Wolter TP, von Heimburg D, Stoffels I, Groeger A, Pallua N. Cryopreservation of mature human adipocytes: in vitro measurement of viability. Ann Plast Surg. 2005 Oct;55(4):408-13. 14. Gröger A, Pallua N. Das Ohr aus dem Labor: Gegenwärtige Einschränkungen bei der Züchtung von Knorpelgewebe. Plastische Chirurgie 2006 (2): 51-54 15. Wosnitza M, Hemmrich K, Groger A, Graber S, Pallua N. Plasticity of human adipose stem cells to perform adipogenic and endothelial differentiation. Differentiation. 2007 Jan;75(1):12-23.
16. Fuchs PC, Bozkurt A, Johnen D., Smeets R, Groger A, Pallua N. Beneficial effect of corticosteroids in catecholamine-dependent septic burn patients. Burns. 2007 May;33(3):306-11. 17. Groger A*, Piatkowski A*, Bozkurt A, Fuchs PC, Pallua N. Acetone associated inhalation injury and rhabdomyolysis. Burns. 2007 Nov;33(7):932-4 *These authors contributed equally to this study. 18. Fuchs PC, Groger A, Bozkurt A, Johnen D, Wolter T, Pallua N. Cortisol in severely burned patients: Investigations on disturbance of the hypothalamic-pituitary-adrenal axis. Shock. 2007 Dec;28(6):662-667. 19. Groger A, Bozkurt A, Piatkowski A, Perez-Bouza A, Fuchs P, Pallua N. Fibromatosis-like myofibroblastic tumour of forearm: Case report and interdisciplinary management. Scand J Plast Reconstr Surg Hand Surg. 2007 Oct 19;:1-3 20. Neuss S, Apel C, Buttler P, Denecke B, Dhanasingh A, Ding X, Grafahrend D, Groger A, Hemmrich K, Herr A, Jahnen-Dechent W, Mastitskaya S, Perez-Bouza A, Rosewick S, Salber J, Woltje M, Zenke M. Assessment of stem cell/biomaterial combinations for stem cell-based tissue engineering. Biomaterials. 2008 Jan;29(3):302-13. 21. Bozkurt A, Tholl S, Wehner S, Tank J, Cortese M, O'Dey DM, Deumens R, Lassner F, Schügner F, Gröger A, Smeets R, Brook G, Pallua N. Evaluation of functional nerve recovery with Visual-SSI-A novel computerized approach for the assessment of the static sciatic index (SSI). J Neurosci Methods. 2008 May 15;170(1):117-22. 22. Groger A*, Grieb G*, Bozkurt A, Piatkowski A, Pallua N. The diversity of carbon monoxide intoxication: medical courses can differ extremely - A Case Report. Inhal Toxicol. 2008 Aug;20(10):911-5. *These authors contributed equally to this study. 23. Groger A*, Bozkurt A*, O'Dey D, Vogeler F, Piatkowski A, Fuchs P, Pallua N. Influencing factors on tissue expansion in reconstructive burn surgery. Burns. 2008 Dec;34(8):1113-8. *These authors contributed equally to this study. 24. Gröger A, Piatkowski A, Unglaub F, Bozkurt A, Pallua N. Merkel cell carcinoma and immunosuppression: report of three cases and review of therapeutic options. Handchir Mikrochir Plast Chir. 2008 Apr;40(2):105-9. 25. Smeets R, Noah EM, Seiferth NY, Gröger A, Bozkurt A, Fuchs PC, Ulrich D, Pallua N. Bioelectric impedance analysis and quality of life after body-contouring procedures in plastic surgery. J Plast Reconstr Aesthet Surg. 2008 Jun 10. 26. Groger A*, Piatkowski A *, Pantel M, Bozkurt A, Fuchs P, Pallua N. Extend of thermal injury has different effects on fractions of mononuclear cells. Burns. 2009 Mar;35(2):256-63. *These authors contributed equally to this study. 27. Kubo T, Randolph MA, Gröger A, Winograd JM. Embroyonic Stem Cell Derived Motor Neurons Form Neuromuscular Junctions in vitro and Enhance Motor Functional Recovery in vivo. Plast Reconstr Surg. 2009 Feb;123(2 Suppl):139S-48S. 28. Groger A*, Grieb G*, Piatkowski A, Markowicz M, Steffens GCM and Pallua N. Tissue substitutes with improved angiogenic capabilities: an in vitro investigation with endothelial and endothelial progenitor cells. Cells Tissues Organs 2010; 191(2):96-104 *These authors contributed equally to this study. 29. Groger A, Piatkowski A, Grieb G, Wolter TP, Fuchs PC, Pallua N. The mobilisation of mononuclear cells and endothelial progenitor cells after burn injury in a porcine model. Burns. 2010 Jun;36(4):545-51. 2. Auszug Vorträge (nur zitierfähige Abstracts)
1. Gröger A, Haisch A, Radke C, Burmester GR, Sittinger M. Polyelectrolyte membrane encapsulation of in vitro engineered cartilage. 2nd Biovalley Tissue Engineering Symposium Freiburg 1999, Abstract published in Cell Tissue Organs 2000; Suppl. 1 2. Haisch A, Gröger A, Sudhoff H, Radke C, Jahnke V, Sittinger M. Polyelektrolytmembranverkapselung von autologen transplantiereten und in vitro hergestellten Knorpeltransplantaten. Jahrestagung der deutschen Gesellschaft für HNO. Aachen 1999, HNO 1999; 47:422 3. Grasnick G, Gröger A, Haisch A, Sittinger M. Polyelectrolyte complex membrane system for in vivo protection of human cartilage implants. Polyelectrolytes Les Diaberets 2000 4. Haisch A, Wanjura F, Endres M, Gröger A et al. Immunmodulation von autogen transplantierten Chondrozyten mit fokal trabekulärer Osteoneogenese. 72. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde Laryngo-Rhino-Otologie, 2001 Suppl. 1. 5. Groger A, Grieb G, Noah EM, Steffens G, Pallua N. Enhancing angiogenetic potential of collagen matrices. 7th conference of young scientist and plastic surgeons. (ECSAPS) 2003 Geneva Switzerland 6. Piatkowski A, Gröger A, Wolter T, Fuchs PC, Woodruff S, Bozkurt A, Pallua N. Die Bedeutung von Endothelvorläuferzellen bei ausgedehntem Verbrennungstrauma. VDPC Düsseldorf 2004. Abstract published Plastische Chirurgie 2004 Suppl. 7. Gröger A, Grieb G, Steffens G, Noah EM, Pallua N. Eigenschaften und biologische Wirkung von modifizierten Kollagen-Matrizes zur Verbesserung der Angiogenese. Jahrestagung der Deutschen Gesellschaft für Chirurgie Berlin 2004. Abstract published Chirurg 2004 Suppl. 8. Gröger A, Piatkowski A, Bozkurt A, Noah EM, Pallua N. Endothelvorläuferzellen als mögliche Zellressource für das Tissue Engineering von vaskulären Strukturen. VDPC Düsseldorf 2004. Abstract published Plastische Chirurgie 2004 Suppl. 9. Gröger A., Piatkowski A., Pallua N. Endothelial Progenitor Cells – a new Promise for Angiogenesis in Tissue Engineering. 15th Endothelial Cell Research Symposium Maastricht 2004. Abstract published Angiogenesis 2004. 10. Gröger A., Piatkowski A., Pallua N. Endothelial Progenitor Cell counts during vascular trauma. 15th Endothelial Cell Research Symposium Maastricht 2004. Abstract published Angiogenesis 2004 11. Gröger A, Piatkowski A., Bozkurt A., Wolter T.P, Fuchs P.C, Woodruff S, Hermanns H, Waltenberger J, Weber C, Pallua N. Isolation of endothelial progenitor cell precursors after extensive vascular trauma. Chirurgische Forschungstage Mannheim 2004. Abstract published Langenbecks Arch Surgery 12. Gröger A, Piatkowski A, Bozkurt A, Pallua N. Endothelial progenitor cells for vascular tissue engineering. Chirurgische Forschungstage Mannheim 2004. Abstract published Langenbecks Arch Surgery 2004 Suppl. 13. Bozkurt A, Lassner F, Groger A, Fuchs P, Heschel I, Pallua N. Engineering of peripheral nerves: an in vitro study. EURAPS 2005 Marseille. 14. Grieb G., Gröger A., Steffens G., Noah E.M., Pallua N. Die Entwicklung von modifizierten Kollagen-Matrizes als verbesserter Dermisersatz für Schwerbrandverletzte. DAV 2005 Davos. 15. Groger A, Piatkowski A, Steffens G, Weber C, Pallua N. Endothelial Progenitor Cells – a new Promise for Angiogenesis in Tissue Engineering. TESI Shanghai 2005. Tissue Engineering Apr 2006, Vol. 12 No. 4
16. Groger A, Smeets R, Haisch A , Sittinger M , Pallua N. Why tissue engineering of cartilage does not work for the human ear and nose: the role of proinflammatory cytokines. TESI Shanghai 2005. Tissue Engineering Apr 2006, Vol. 12 No. 4 17. Groger A, Piatkowski A, Steffens G, Weber C, Pallua N. Endothelial Progenitor Cells for Angiogenesis in Tissue Engineering. Annual TERMIS-EU Meeting, Tissue Engineering & Regenerative Medicine International, European Chapter, Rotterdam , Netherlands , 8-11 October 2006 18. Groger A, Smeets R, Haisch A , Sittinger M , Pallua N. New insights on autologous cartilage rejection. Annual TERMIS-EU Meeting, Tissue Engineering & Regenerative Medicine International, European Chapter, Rotterdam , Netherlands , 8-11 October 2006 19. Groger A, Pallua N. Angiogenesis in Tissue Engineering presented at CORTE Rom May 2006 20. Groger A, Pallua N. Adipose Tissue Engineering. IQUAM Consensus Conference Regensburg 2006 21. Groger A, Pallua N. Tissue Engineering with preadipocytes. Annual meeting of Spanish society for plastic surgery Pamplona 2006 22. Groger A, Smeets R, Haisch A , Sittinger M , Pallua N. Der Einfluss von pro- inflammatorischen Zytokinen auf die Resorption von gewebetechnologisch hergestelltem Knorpelgewebe. DGPRÄC Aachen 2006. Plastische Chirurgie 2006 Suppl. 23. Piatkowski A., Gröger A., Bozkurt A., Pallua N. Mobilization of endothelial progenitor cells after flap procedures. 17th Endothelial Cell Research Symposium Maastricht 2006 Abstract published Angiogenesis 2006 24. Wosnitza M, Hemmrich K, Groger A, Graber S, Pallua N. Plasticity of human adipose stem cells to perform adipogenic and endothelial differentiation. ECSAPS 2006 London 25. Wosnitza M, Hemmrich K, Groger A, Graber S, Pallua N. Innovative Tissue Engineering Possibilities by exploiting Stem Cell Plasticity of the Adipose Stromal Vascular Fraction. ESSRR Rostock 2006 26. Wosnitza M, Hemmrich K, Groger A, Pallua N Innovative Tissue Engineering Possibilities by exploiting Stem Cell Plasticity of the Adipose Stromal Vascular Fraction.International Society for Cellular Therapy Annual Meeting, Berlin, Germany, 2006. Abstracts. Cytotherapy. 2006;8 Suppl 1: 80 pages (Impact(2004)=1.392, Typ=Meeting Abstract 27. Wosnitza M, Hemmrich K, Gröger A, Pallua N. Human adipose tissue progenitor cells allow combined engineering of fat tissue and endothelial structures. Abstracts of the 2nd International Conference of Strategies in Tissue Engineering, May 31-June 2, 2006, Wurzburg, Germany.Cytotherapy. 2006;8 Suppl 2: 3-67 Impact(2004)=1.392, Typ=Meeting Abstract 28. Neuss S., Apel C, Denecke B., Gröger A., Hemmrich K., Perez-Bouza A., Salber J., Wöltje M., Zenke M. The new biomaterial platform for stem cell-based applied tissue engineering at RWTH Aachen University. Stem Cell Meeting Düsseldorf 2006 29. Perez-Bouza A., Apel C, Denecke B., Gröger A., Hemmrich K., Salber J., Wöltje M., Zenke M., Neuss S. Stem cells meet biomaterials: A new research platform at the RWTH Aachen University. 91. Jahrestagung Deutsche Gesellschaft für Pathologie 30. Neuss S., Apel C, Denecke B., Gröger A., Hemmrich K., Perez-Bouza A., Salber J., Wöltje M., Zenke M. Grid-based platform to assess basic compatibility of stem cell/biomaterial combinations. IZKF Meeting Kerkrade 2007 31. Gröger A. , Kubo T., Randolph M. , Winograd J, Pallua N. Three dimensional growth and function of embryonic stem cell derived motor neurons in biodegradable hydrogels. 53rd Annual Meeting PSRC 2008, Springfield, IL
32. Groger A, Randolph, Yaremchuk M, Haisch A , Sittinger M , Pallua N. Why tissue engineering of cartilage does not work for the human ear and nose: the role of proinflammatory cytokines.12 th ECSAPS 2008 Bern 33. Gröger A., Kubo T., Randolph M. , Winograd J, Pallua N. Motorneurone aus embryonalen Stammzellen bilden neuromuskuläre Endplatten in vitro und in vivo. DGPRÄC 2008 Stuttgart 34. Gröger A., Kubo T., Randolph M., Winograd J, Pallua N. Motorneurone differenziert aus embryonalen Stammzellen bilden neuromuskuläre Endplatten In Vitro und verbessern die funktionelle motorische Regeneration In Vivo. DGCH München 2009 35. Gröger A., Kubo T., Randolph M. , Winograd J, Pallua N. Tissue Engineering mit embryonalen Stammzellen und Gel basierten Biomaterialen. DGPRÄC 2009 Hannover 36. Gröger A. , Kubo T., Randolph M. , Winograd J, Pallua N. Three dimensional growth and function of embryonic stem cell derived motor neurons in biodegradable hydrogels. 13th ECSAPS 2009 Rotterdam 37. A. Gröger &N. Pallua. Narbenbehandlung mit Lipofilling: Die Ergebnisse einer Klinischen Studie. DGPRÄC 2010 Dresden 3. Sonstiges
Preise/ Auszeichnungen
1. Fellowship Division of Plastic Surgery, Massachusetts General Hospital, Harvard University, Boston, USA 2. 1°-Place Research Grant Award der American Society Maxillofacial Surgeons (AMAS) 2007 3. 1°-Place Massachusetts General Hospital Surgical Medpore Research Award 2007 Buchbeiträge
1. Pallua N & Gröger A. Tissue Engineering und Keratinozyten- Züchtung als Beispiel der experimentellen Forschung in der Plastischen Chirurgie. Chirurgische Forschung, Thieme Verlag, Krugemeyer/Spiegel (Hrsg) 2006; 237-261 2. Pallua N & Gröger A. Tissue Engineering and Plastic Surgery. Innovations in Plastic and Aesthetic surgery. Eisenmann-Klein, M.; Neuhann-Lorenz, C. (Eds.) 2008; 17-23 Patente
1. Gröger A, Wanjura F, Haisch A, Sittinger M. Autologe Bindegewebe, Verfahren zu ihrer Herstellung und ihre Verwendung. DE 100 38 700 84 2006.09.07 Deutsches Patent 2. Gröger A, Wanjura F, Haisch A, Sittinger M. Autologe Bindegewebe, Verfahren zu ihrer Herstellung und ihrer Verwendung. PTC/DE 01/02899 Internationales Patent 3.Gröger A, Wanjura F, Haisch A, Sittinger M. Mittel zur Verringerung der Abstoßungsreaktion bei gewebetechnologisch hergestellten Transplantaten. PTC/DE 01/02900 Internationales Patent
d e n i n g y o u r p o i n t o f v i e w Richard Bach, in his book Illusions , states a handy aphorism: Perspective – use it or lose it . This periodical shares amongst recreation and tourism management professionals, and others, several tools and concepts which will help exercise your perspective. This issue considers measuring the past and predicting the future. It is also th
Enantioselective Synthesis of a-Hydroxy Ketones via Benzaldehyde Lyase-Catalyzed CÀC Bond Formation ReactionAyhan S. Demir,a,* ÷zge SÀesÀenoglu,a Elif Eren,a Birsu Hosrik,a Martina Pohl,b,dElena Janzen,b Doris Kolter,c Ralf Feldmann,c Pascal D¸nkelmann,c Michael M¸llerc,*Department of Chemistry, Middle East Technical University, 06531 Ankara, Turkey,Fax: ( 90)-312-2101280, e-mail: asdem