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SIGMA-ALDRICH
sigma-aldrich.com
Material Safety Data Sheet

1. PRODUCT AND COMPANY IDENTIFICATION
Sigma-Aldrich 3050 Spruce Street SAINT LOUIS MO 63103 USA
2. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards
Target Organ Effect, Harmful by ingestion., Teratogen
Target Organs
GHS Label elements, including precautionary statements
Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Dispose of contents/container to an approved waste disposal plant. HMIS Classification
Health hazard:
Chronic Health Hazard:
Flammability:
Physical hazards:
NFPA Rating
Health hazard:
Reactivity Hazard:
Potential Health Effects
Inhalation
May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. Ingestion
Sigma - S8260

3. COMPOSITION/INFORMATION ON INGREDIENTS
α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol Albuterol Salbutamol
18559-94-9 242-424-0

4. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

5. FIRE-FIGHTING MEASURES
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.

6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Keep in suitable, closed containers for disposal.

7. HANDLING AND STORAGE
Precautions for safe handling
Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place.
Sigma - S8260
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Contains no substances with occupational exposure limit values. Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1
(EN 143) respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with gloves.
Eye protection
Safety glasses with side-shields conforming to EN166
Skin and body protection
Choose body protection according to the amount and concentration of the dangerous substance at the work place.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of
workday.

9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Safety data

10. STABILITY AND REACTIVITY
Chemical stability
Stable under recommended storage conditions.
Conditions to avoid
no data available
Materials to avoid
Strong oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx)

11. TOXICOLOGICAL INFORMATION
Acute toxicity
LD50 Oral - rat - 660 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
Sigma - S8260
Respiratory or skin sensitization
no data available
Germ cell mutagenicity

no data available
Carcinogenicity
No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Reproductive toxicity
May cause congenital malformation in the fetus.
Reproductive toxicity - mouse - Subcutaneous Effects on Newborn: Biochemical and metabolic. Reproductive toxicity - Human - female - Oral Maternal Effects: Uterus, cervix, vagina. Developmental Toxicity - rat - Intravenous Effects on Embryo or Fetus: Other effects to embryo. Specific target organ toxicity - single exposure (GHS)
no data available
Specific target organ toxicity - repeated exposure (GHS)
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation
May be harmful if inhaled. May cause respiratory tract irritation. Ingestion
May be harmful if absorbed through skin. May cause skin irritation. Signs and Symptoms of Exposure
Tremors, Palpitation, Headache, To the best of our knowledge, the chemical, physical, and toxicological properties have
not been thoroughly investigated.
Additional Information
RTECS: ZE4400000

12. ECOLOGICAL INFORMATION
Toxicity
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
Sigma - S8260
PBT and vPvB assessment
no data available
Other adverse effects

13. DISPOSAL CONSIDERATIONS
Product
Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service
to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator
equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

14. TRANSPORT INFORMATION
DOT (US)
Not dangerous goods
IMDG
Not dangerous goods
IATA
Not dangerous goods

15. REGULATORY INFORMATION
OSHA Hazards
Target Organ Effect, Harmful by ingestion., Teratogen
DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold
(De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards
Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components
New Jersey Right To Know Components
California Prop. 65 Components
This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other
reproductive harm.

16. OTHER INFORMATION
Further information
Copyright 2010 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only.
Sigma - S8260
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. Sigma - S8260

Source: http://www.westernunew.com/bin/safety/msds/urc/Salbutamol.pdf