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SERUM BIOMEDICAL INSTITUTE – ADVANCED IVF TREATMENT TREATMENT INFORMATION – Donor Cycles

Donor Egg protocols:

Depending on the time of your cycle, the donor’s cycle, and our judgement of what will best suit your body, we normally have 3 possible options: 1. Natural cycle 2. Semi-medicated cycle 3. Medicated (fully down-regulated) cycle.
Natural cycle:
We use your natural menstrual cycle and aim for your ovulation to coincide with your donor’s egg collection. Your body supplies the natural estrogen and then the progesterone you need to prepare your lining, but we may add progesterone to your programme (e.g. Utrogestan / Cyclogest / Crinone gel etc.) if your blood tests show you need it after ovulation, or if from your history we guess you might need it without blood tests. We often find that using a natural cycle can give a better lining for patients who have struggled to develop an adequate lining on a previous medicated cycle.
Semi-medicated cycle:
You start oestrogen (Progynova / Cyclacur white) near to the start of your cycle, and then we add progesterone, usually the day after the donor has had her egg collection. Egg collection is usually about 10-16 days after you start your oestrogen and your donor starts her stimulation.
Medicated (down regulated) cycle:
On a full down-regulated cycle, you take a drug like Arvekap / Prostap (usual y monthly injections of 3.75mg or 3 monthly injections of 11.25mg) to down-regulate your body for 2 weeks to 3 months before you start your The down reg injections are started on day 21 of a normal cycle, or if you are still on IVF meds (e.g. Progynova / Cyclacur and Utrogestan) you can usually start immediately, provided you continue to take the IVF meds for about 7 days overlap to prevent your body restarting your own natural cycles before the down regulator takes effect. Otherwise, you can start a down reg on about day 3 of your cycle, but you won't be fully down regulated until your own cycle has ended, as your body may continue to ovulate that cycle and make its own hormones. All down reg drugs produce an initial surge in hormones (LH and FSH), but after about a week your hormone levels will start to drop, and within about 2 weeks (longer if you start DR on day 3), you will have a bleed and then your lining will stay thin as your cycles will be shut down (for as long as the down reg drug lasts). You can stay in this state indefinitely (if necessary having repeated monthly or 3 monthly shots), and you wil start your oestrogen medication to build up your lining again whenever both you and the donor are ready. After the bleed, you should notice some (menopausal) signs to give you some reassurance that you are down regulated e.g. headaches, hot flushes (particularly at night) and your cervical mucus should remain thin, fairly dry and white-ish (not profuse, clear and egg white like). If you have these signs and they stop, please let us know. If you experience headaches, please remember to drink plenty of water and take paracetamol if needed. On a long down regulated cycle, we may recommend a scan just before you are due to start oestrogen to check that you have stayed down-regulated i.e. your ovaries are still quiet, and your lining is still thin, to make sure you are ok to start your oestrogen that week. If you have obvious menopausal signs, the scan may not be needed.
Scans:
On all donor egg cycles, we may recommend that you have an ultrasound scan on about day 11 of your oestrogen / natural cycle, to make sure your lining is thickening up properly. If you have had problems with lining thickness on previous cycles, we may recommend an earlier scan than this. You do not need to come to Greece for this, but it may be worth finding out in advance where you can get a scan in your home country, in case you need one. Below we have listed some of the places in the UK previous clients have used: • In London there are many places to get a scan e.g. the Birth Company on • In Bristol, some of our clients have used Dr Valentine Arkande's clinic; • In Leeds, some ladies use The Leeds Screening Centre (trading as “This- • In other areas, you may want to ‘phone your local private pregnancy ultrasound clinics and see if they can do a transvaginal ultrasound, but please note that some clinics only have the equipment to do an abdominal ultrasound (the type used in pregnancy), which isn't good enough to see the lining; • Or you can try your local private hospital e.g. BMI or Spire gynae
Additional medication:
Depending on your fertility history, we may recommend additional medications
for your cycle. Here you will find examples, but note that the medications we
recommend for you will be based on your particular case:
• On all semi-medicated and medicated donor egg cycles Progynova 2mg (oestrogen) is taken. The Greek equivalent is Cyclacur 2mg (the white tablets only); • On most donor egg cycles you will need some progesterone support after egg collection day with e.g. Utrogestan (pellets which are normally taken vaginally but can be used orally if necessary), Cyclogest pessaries, or Crinone gel. Some women will need additional support from Gestone or Prontogest shots (particularly after embryo transfer); • All women are advised to take 5mg Folic acid / Fillicine throughout the time they are planning to conceive or pregnant. • For immune issues you may be advised to take Prednisolone / Methylprednisolone / Medrol in doses from 4mg to 32mg • For clotting issues you may be advised to take Clexane shots (40mg, 60mg or 2 x 40mg) from the start of oestrogen or stimulation • Some women with a viral history will be advised to take 500mg Valtrex / Valaciclovir twice a day from the start of natural cycle/oestrogen for 10 days • Some women with an infection history will be advised to take 100mg Doxycycline / Vibramycin (or erythromycin) twice a day from the start of natural cycle/oestrogen until embryo transfer or until pregnancy test day. • Some ladies will be advised to take vaginal Viagra cream twice a day from part way through oestrogen administration until embryo transfer.
When do we need to be in Athens?
We will always tell you as far as possible in advance when you can book your flights. But please do bear in mind that we are often unable to give you as much notice as you and we would like, as exact dates will depend to a large extent on: • your donor’s menstrual cycle; and • when she is ready for egg collection (“EC”). We try to work with our donors’ natural cycles to give recipients the best-quality embryos for the best chance of pregnancy, and accordingly, we will only be sure that a donor is ready to start her stimulation medication when her period arrives and we have seen her for baseline scan. In our experience, even donors who normally have very regular periods often experience an unexpectedly delayed period when they are due to be starting their donor cycle due to the anticipatory stress, so it’s not uncommon for donors to be delayed in starting and it is unhelpful for the donor’s stress levels (and therefore her egg quality) if we keep chasing her to find out if there are any signs of her impending period. We will always let you know that the donor is ready as soon as we know ourselves. The optimal length of stimulation will vary from donor to donor. Typically it will be 12 days from starting stimulation to Egg Col ection, but it may vary from 10-16 days. We can only be certain of the exact date that EC will definitely take place 2 days before EC i.e. when we issue your donor’s trigger shot. After the trigger shot, the donor has a ‘drug-free’ day, and then the EC takes place the following morning. Additionally, for women with common physical characteristics, there will often be more than one possible donor due to start within a few days of each other. Again, to give you the very best chance of pregnancy, it is better if we can retain some flexibility over which donor we choose for you, based not just on their characteristics, but also in terms of their response to stimulation and exact timing of EC, compared to how your own cycle and lining has developed. Sometimes we may also recommend blood tests to check your hormone levels to help us make a final decision. So our view about the best possible choice for you may well change between the start of your cycle and a donor's EC. For this reason, we prefer not to confirm information about your donor until EC, but please be assured, if you have specified any non-negotiable donor characteristics, we will only consider donors for you who meet those requirements. Obviously, if you are relatively flexible, and have common physical characteristics, we will have a larger possible choice of donors for you. For all of the above reasons, we advise you not to book your flights to Athens until we get to trigger shot day (which gives the female partner 3-7 days to get to Athens for transfer; and the male partner 2 days if he is giving a fresh sperm sample). If you are unable to work within such a timeframe, e.g. you are unable to book time off work at such short notice, please let us know your travel plans, and we will try to accommodate them. But it may mean you need to stay in Athens for a slightly longer period, to allow us the flexibility we’ll inevitably need over dates. Obviously, for the male partner, freezing a sample of sperm with us in advance may make the process easier. We advise you not to book your flight home until at least the day after EC, when we will be able to advise you whether a 2-, 3- or 5-day transfer is likely. We are aware of the frustrations that such uncertainty can cause you, and as such will always do our utmost to ensure you have as much notice as possible as to how your donor’s cycle is progressing. We can also offer the following general guidance to help you with your planning:
Natural cycles:
This requires that there is at least one matching donor cycling who is expected to have EC at around the time of your ovulation – so you will need to be in touch with the clinic on the day that your period starts to see if there is at least 1 possible matching donor for you. We will estimate your ovulation based on your previous cycles – either by assuming that it’s about 14 days before your period, or because you've previously been monitoring your cycles using LH urine sticks (“OPKs” – ovulation predictor kits). Ovulation normal y takes place about 24-48 hours after a positive stick test. If you have monitored your cycle with an OPK, you will be aiming to have embryo transfer about 4-5 days after you see a positive result. If your partner is providing fresh sperm, he will need to be in Athens on the day of EC – so he will get about 2-3 days’ notice of when he needs to be here. Medicated cycles:
You will either be starting oestrogen medication on about day 2 or 3 of your natural period, or, if you have down-regulated, we will agree with you the best time for you to begin according to your donor’s cycle. Your donor will start her stimulation drugs at the same as you start your oestrogen. EC is typical y on day 12 of the stimulation drugs / oestrogen, but it can be a few days earlier or later than that. Additionally, if there is more than one possible donor matching your criteria due to be cycling within a couple of days, we may decide to delay the decision on which is the best donor to choose for you until EC, so we can see how the response to stimulation has been and how your lining has developed. If your partner is giving a fresh sperm sample, he will need to be in Athens on the day of EC, but there will only be absolute certainty about the date 2 days beforehand i.e. when your donor is given her trigger shot. So if he can wait until 2 days before EC before booking his flights then he can have certainty. Otherwise, he will need to be available possibly from day 10-16 from when you start estrogen, or he may be better to freeze a sample of sperm with us in advance. Embryo transfer will usually be on day (2), 3 or 5 after EC.
Frozen transfers:
For a frozen transfer on a natural cycle, we would expect you to need to be in Athens for your transfer approximately 4-5 days after seeing a positive LH on an OPK.
Our egg donors:

Ethnicity
For matching UK recipients, we usual y choose from among our blonde or brown-haired eastern European donors. They are often from Poland or the Ukraine, and are economic migrants to Athens working in e.g, healthcare or hotels, often sending money back to their families at home. As such they are often well educated and over-qualified for the work they do in Athens. They tend to be motivated 'self-starters', who have chosen to move to a new country for better prospects. They are usual y in their twenties, and many of them have young children of their own, so also choose to donate to earn extra money for their own families here in Greece. We also have many Greek egg donors, often university students. These tend to be more suitable for dark-haired/brown-eyed recipients. Red-haired donors may be more difficult to find as they are unusual in Athens and our preference is not work with red-haired donors due to the increased risks of clotting problems that are sometimes associated with red hair. Other ethnic matches may be possible, e.g. there is a large Asian population in Athens, but whether any such donors are available depends on whether and when any show up at our clinic. We also have a few Afro-Caribbean donors on our books. Recruiting donors
Donors are recruited by word-of-mouth only – advertising for donors is not legal in Greece. So donors tend to be friends of previous donors who become familiar with the process whilst their friend is donating. We are careful about which donors we will accept on our programme, but once they join, we tend to have a long-term relationship with them. All donors are screened for infection and for Karyotyping. We also extensively review each potential donor’s family medical history before we accept them. We only accept donors who have a clean family medical history; are normal weight; and who we are satisfied are mentally stable. The resulting babies from any donor treatment are very important to us. We believe that beautiful and intelligent people tend to have better lives, and that beautiful children will tend to fit better into families, so we only accept donors whom we judge to be beautiful! How are the egg donors treated?
It is important to us to look after our donors well. We usual y have long-term relationships with our donors; we get emotionally attached to them; and would never want to compromise their health and wellbeing. In any event, we feel that egg quality is compromised by being overly aggressive with stimulation drugs, so our approach is always to give the minimum level of drugs to aim for about 8-10 eggs for the recipient, but not more than this. Our donors are treated in the same building and given a similar level of care to that of their recipients and our own egg patients. Note, however, that because egg donation is anonymous, it is unlikely that you will be in the building at the same time as the donor. If your partner is arriving at our clinic on the day of your donor's EC to give his sperm sample, we will generally ensure this happens at a different time, so neither you nor he will not bump into your donor while you are there. If you are coming to the clinic just for ET, your donor will obviously have finished her part of the cycle 2-5 days before your visit. Most of our donors are comfortable with their first treatment so are happy to return to be egg donors again, though we do not like them to do more than 4 or 5 cycles in any 2-year period – and there is a limit under Greek law of 8 resulting babies per home country per donor. Our donors receive about €1,500 per cycle, as compensation for their expenses
and lost earnings etc.
Our sperm donors:

Our sperm donors are often young Greek men – blonde, brown or dark-haired.
We also have a few afro-carribean donors. Again they are personally known to
us and are recruited by word-of-mouth, so by recommendations of friends.
If a different ethnic match is required e.g, from an Asian origin donor , we can also access sperm from a commercial cryobank at cost, but for sperm that is from our local donors and already in our bank, there is no extra charge if you are doing a donor egg cycle. All donors are screened for infection (every 3 months) and family medical history
and karyotype, and the information recorded about them is similar to that
recorded for egg donors. All sperm samples are quarantined for at least 6
months as required by law.
Can we use both en egg and a sperm donor?

Yes, you can. You can use:
• a full egg donor cycle with donor sperm; • back-up donor fresh embryos if a suitable match is available to fit in with • frozen embryos created from donor egg and sperm from our embryo bank (we call this “embryo adoption”). Due to the economic crisis in Greece, at the moment there are more donors available than recipients, partly because Greek couples are struggling to afford fertility treatment, but also because so many donors are wanting to donate to find extra money to support their own families. We recruit all our donors by word-of-mouth only (friends of donors tend to want to become donors themselves), and, over time, we have got to know our donors very well and are reluctant to turn them away when they are in financial need. This means that there are many fresh back-up donor cycle embryos fertilised with donor sperm that go straight into our frozen bank, but would be available at short notice to women whose natural cycle fits well with the timing of the donor cycle. We are strongly in favour of natural cycle donor IVF for suitable women, so to
use the 'backup donor embryo rescue programme', after your initial consult, all
you need to do is to let us know when your period starts (and the normal length
of your cycles) to see if there is likely to be a back-up donor available when you
need her, who is a good physical match for you.
What is the matching process?

The law in Greece
Donation is strictly anonymous in Greece, so use our best judgment as to which donors are a suitable match for you. It has never happened to us, but in the event that a child born from egg or sperm donation developed a medical condition for which knowing their genetic parents may help their health e.g. they were trying to trace genetic family for an organ transplant, there is provision under Greek law to overturn the anonymity rule for this purpose. In common with all Greek fertility clinics, we keep detailed records on all our donors. Under Greek law, if a clinic were to close down, these records have to be transferred to another clinic to ensure that they are always preserved. As an additional precaution, we also keep on file a DNA sample from each donor, which can be made available to the recipient should a need for it arise in the future. So if you later needed or wanted to know more about the donor's genetics, you could have this sample analysed. You would of course still not know your donor's name, but this provides you with extra security and peace of mind in case of medical need, in the event your donor had died or could not be traced. How we match you
Before you have an initial consultation with us, you will fill out forms detailing your medical history. You will also send us photographs of yourself, your partner, and any children you already have so that we have these in front of us When you ask us to find you a donor, you may also want to give us a list of the non-physical characteristics that are most important to you. We will never compromise on the basic physical characteristics needed for a match – that is, hair colour, eye colour etc. – but bear in mind that the bigger the list of additional criteria you give us that need to met, the lower the number of potential donors who can be considered for you, and therefore the longer you are likely to have to wait for a suitable donor to be found. When matching a donor for a couple, a knowledge of which physical traits are dominant is also relevant. E.g. if your eyes are blue, but your partner has brown eyes, the brown eye trait would often dominate if you had a natural child, so your own eye colour might be less relevant in this case. If you are doing a full donor egg cycle, we may be able to tell you which of your criteria we have matched in the proposed donor at the start of your cycle and will be able to answer any (reasonable) questions you have about the donor to the best of our knowledge about them. But at the moment, we have so many donors available, that at the start of your cycle we may well have more than one possible donor in mind for you, and will prefer to wait until the day of EC before deciding which donor we feel is going to be the best choice for you. Accordingly, it makes more sense to wait until at least EC before having a detailed discussion about your donor. You will always have the opportunity to discuss the donor in detail before the transfer on the day of ET. Please be assured though, if you have specified particular non-negotiable criteria, we will only consider donors who meet these criteria for you. We strongly believe that matching a donor is more than just physical
characteristics – we try very hard also to match on our instincts of what donor
child might 'fit' into your family.
What criteria can I ask for a donor to meet?
We will always endeavour to match on the main physical characteristics (hair colour, eye colour, race/approximate skin tone). Our patients sometimes ask us to try and find a donor with a particular blood group, weight or height range (although, of course, we cannot accept overweight donors onto our programme), physical build, education level, nationality, personality type, broad hobbies/interests. However, the more characteristics you require us to meet as non-negotiable, the fewer donors we will be able to consider for you. What information is available about the donors?

As detailed above, donation is strictly anonymous in Greece. Before we can go
ahead with your treatment, you will be asked to sign a form agreeing that you
will never know the donor’s identity.
However, we screen all prospective donors personally; we do their scans; we look after their stimulation; and we do their egg collections. We therefore get to know our donors very well. We also keep a file on each of our donors, containing basic information such as: • height • weight • nationality • hair colour • eye colour • blood group • profession • family medical history • other children/fertility history • donation history. We can also give you our own impressions of the donor having met her. So although your donor wil always be anonymous to you and to your child, you probably end up with more (non-identifying) information about your donor from us, than you would receive from a UK donor clinic. If you are doing a full donor egg cycle, we will be able to tell you basic information about your donor at the start of the cycle – but, unless you have more unusual criteria, there will often be more than one possible egg donor at the start of your cycle, and, if that is the case, we usually prefer to delay making the decision on which donor fits you best in terms of matching criteria and timings until a donor reaches her trigger shot day (2 days before her EC). If you choose the back-up donor option, the same detailed information will be available to you, but possibly not until just before ET. Most couples have a consultation with us to discuss the donor either on EC day if the male partner is providing fresh sperm, or otherwise on the day of ET. If you prefer, you can choose not to ask about your donor until you know if your cycle has been successful, but that is your choice. Clients who aren't lucky on their first cycle often find that they want to know everything possible about their donor on their first cycle, but by their second cycle, they are so comfortable with us they would prefer to leave it to us, and wait until there is a confirmed pregnancy before asking for information about their donor. Obviously, to preserve the donor's right to anonymity, you must not post any identifying information about your donor on the Internet. And if you decide to leave a card or a gift for your donor, as many of our clients do, you must not include on it any information that identifies you.
Can I see a photo of the donor, their baby photo’s or photo’s of
any of their children or offspring of previous donations ?
No. Greek law does not permit us to release any identifying information.

Are the donors proven ?
On our main donor programme, we only use proven donors (donors who have
successfully donated before with us) and produced either a donor pregnancy or
at least a good number of high quality embryos. On our back up donor
programme, some of our donors may be cycling with us for the first time.
Can I do IUI/DIUI at Serum?

Yes. It is possible to do either
• IUI with your partner's sperm; • DIUI with donor sperm; or • combine treatments in the same cycle e.g, DIUI and Donor egg/Donor This would mean having an insemination just before ovulation and then having ET a few days later and would give you the possibility of becoming pregnant with your own egg (and the inseminated sperm) or with the donor egg/embryo. You wouldn't be sure until your baby was born who is the genetic mother of the child – and by the time your baby arrives you may well feel it is not something you need to ever want to know. But if you wanted to be sure, it is very simple and not expensive to test your baby using a cheek swab genetic test to compare with your DNA, and you can do this privately if you want keep the outcome confidential. Can I do a tandem OE and DE cycle at Serum?

Yes, in theory you can do this, but this may be an unsatisfactory compromise.
Trying to tie in the exact length of your OE stimulation with a specific donor's
stimulation could be difficult, and it could mean that one of you ends up with a
less than ideal length of stimulation, or you end up missing your implantation
window (the time when your lining is capable of accepting an embryo).
Additionally, if you wish to do this, we would need to charge you the full cost of
an own egg and a main donor cycle (except if the own egg cycle does not
proceed to egg collection, we usually make no charge for the own egg cycle).
However, if you do an own egg cycle and things do not look promising by EC/ET day, it is usually the case that we have an “un-booked” back-up donor available, who is a suitable match for you (depending on your characteristics). In this case it would be possible for you to switch to a donor egg cycle at the last minute. If not, you would hopefully be able to do a donor cycle starting on your next
period. This option may give you a better chance of success, as some women
have a better implantation window if their hormone levels aren't raised as much
as can happen during an OE cycle.
Is there an age limit for donor treatment?

Yes. You can have fertility treatment in Greece up until your 51st birthday.
Is there a weight limit for donor treatment?

No. In the interests of your own health and that of your babies, we would
encourage all our clients to be as close as possible to a healthy weight, but we do
not turn women away on the basis of a high BMI.
Do you treat single women or F/F couples or work with
surrogates?

Yes.

Can I freeze any spare embryos?
Yes – on a full main donor cycle. But there is an additional charge (see below). We will only advise that you freeze embryos if the quality seems adequate.
What method do we use for freezing embryos?
We use vitrification. If you have done a day 3 transfer and the quality is excellent, we will tend to suggest freezing day 3 embryos. If the quality is borderline, we may suggest taking the embryos to blastocyst to ‘test’ their quality so that you do not incur a cost for freezing embryos if there is little chance that they are capable of producing a pregnancy.
Do you offer ICSI/IMSI?
Yes. There is no additional charge for this, but we do everything we can to avoid
using it as IVF is a more natural method of fertilization than ICSI/IMSI and there is
a small increased risk of birth defects where ICSI/IMSI is used compared to IVF.
If we feel there are interventions we can suggest to improve the quality of the
sperm before your fertility cycle in order to increase the chance that we can use
IVF rather than ICSI we will do this. Our embryologist also performs screening
tests either on the day of the egg collection or before the sperm is frozen to
assess its suitability for IVF rather than ICSI to help us make the best decision,
and for samples which are borderline, if there are sufficient eggs, our
embryologist may suggest using IVF on half the eggs and ICSI on the other half, to
increase the chance that we will have some IVF embryos we can transfer.

Do you offer donor sperm?
Yes. There is no additional charge if you are doing IVF with us provided we have suitable sperm in our own bank from our local sperm donors. Our sperm donors are infection screened every 3 months and karyotyped and the sperm is quarantined (as required by law) for at least 6 months. If we do not have suitable sperm from local donors to match your requirements e.g,. from an Asian origin donor, we can source it from a variety of sperm banks. The cost will vary according to which bank we need to use and the delivery charges etc but we do not charge any mark-up.
Do you offer Sex Selection?
No.

Can we ship sperm from an International Bank or another clinic?
Yes. The bank or your other clinic should be able to help you arrange this. You will normally need to supply at least 1 straw/vial per IVF treatment. If you choose to leave sperm in our bank for more than 1 year, we may need to charge a storage fee.
Can we ship sperm from an International Bank or another clinic?
Yes. The bank or your other clinic should be able to help you arrange this.
Costs:

Full egg donation – €5,000
A donor egg or double donor (donor egg with donor sperm) cycle with us costs €5,000. This excludes the cost of your medication and any blood tests you may need, but if you are using your partner’s sperm, it includes whatever “extras” our embryologist feels will benefit you on the day e.g. ICSI or IMSI etc. In the event that your cycle does not proceed to embryo transfer due to a problem with the donor, we will usually waive all our charges. In the event that your cycle does not proceed to embryo transfer due a problem with your lining development, we will try to work with you to get your lining in line and, if necessary substitute another donor with a later egg collection to allow more time to develop your lining if we can, but once the donor has started her stimulation we reserve the right to charge our full cycle cost if you decide to cancel, if you are unable to travel or unable to have embryo transfer due to a problem with your lining or your partner’s sperm. Freezing / follow-up Frozen Embryo Transfers – €1,000
If you wish to freeze any spare embryos from your full egg donation cycle, the cost is €1,000. This includes the cost of any follow-up frozen embryo cycles (consultations, scans, transfers but not any medication or blood tests that may be needed) If we agree to do both a day 3 and a day 5 transfer (‘interval double transfer’) for you in the same cycle we will make no charge for the second transfer if you are also freezing spare embryos – otherwise we charge €300 to do a second embryo transfer. Back-up donor programme – €3,000
We offer a back-up donor programme, giving you 3 grade 1 embryos, for €3,000. Whenever we are running full donor cycles, we simultaneously run back-up donors with similar physical characteristics, in case a problem develops with a main donor, and she needs to be replaced. Most of the time the back-up donor is not required, so her eggs can be made available to another client of a reasonable match, ready to cycle at short notice on this programme. On this programme we offer to match on main physical characteristics only (hair colour, eye colour, ethnicity). Obviously, there is a chance that your cycle will be cancelled if the back-up donor is needed on the full cycle, but in reality this risk is usually small. Double donor embryo adoption – €2,000
Using frozen embryos created from back-up donor eggs and donor sperm costs €2,000. Again this does not include the cost of your medication. Donor sperm – €free of charge
We do not charge for donor sperm, if using sperm from our own sperm bank.
Payment terms:

Please pay 50% by bank transfer when your donor starts her stimulation drugs;
and the remaining 50% by ET either in cash or by card at the clinic. Please see
our information sheet on how to pay for more details.
We believed this information was correct at May 2012 but our views and our

Source: http://www.serum-ivf.com/documents/donor_egg_protocols.pdf