Curriculum vitae

Dr. Daniel R. Jones
4201 South Washington Street Marion, IN 46953 Telephone: 765-677-2296 Fax: 765-677-2455 E-mail: [email protected] 9389 Rockwood Court, Noblesville, IN 46060 PERSONAL:


CAREER SUMMARY:
I have been blessed with opportunities to learn and serve in the dental, biomedical research, and teaching fields. I am most grateful for the opportunity to serve Christ at Indiana Wesleyan University, integrating my faith with my work in the biomedical field by teaching, advising, and involving undergraduates with research.
EDUCATION:
1984
D.D.S., Indiana University School of Dentistry Ph.D., Biomedical Science, Wright State University
POSITIONS:
1987-1990
Doctoral student/teaching assistant, Wright State University Post-doctoral research fellow, Eli Lilly and Company Adjunct pre-nursing physiology instructor, Indiana University- Post-doctoral research scientist, Indiana University School of Medicine/Indiana University School of Dentistry Adjunct first year dental student problem-based learning instructor, Assistant Professor of Biology, Indiana Wesleyan University Associate Professor of Biology, Indiana Wesleyan University Professor of Biology, Indiana Wesleyan University
HONORS AND AWARDS:
2006
Gallup Organization Strengths-Based Curriculum Implementation
SCIENTIFIC PRESENTATIONS:
2006
Poster presentation: CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay, 122nd Annual Indiana Academy of Science Fall Meeting, Ball State University, Muncie, Indiana Oral presentation: A Bare Bones Update on Osteoporosis Research at IWU, John Wesley Honors College Faculty Lecture Series Poster presentation: CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay, Federation of American Societies for Experimental Biology Meeting, San Diego, California Oral Presentation: Physiological Levels of the Potential Anti-
Osteoporosis Agent, Reveromycin A, do not Induce Apoptosis or
Necrosis of Chondrocytes at pH 7.4, 128th Annual Indiana Academy
of Science Meeting, Indianapolis, Indiana 4

MENTORED SCIENTIFIC PRESENTATIONS:
2004
2nd Annual IWU Celebration of Scholarship: Optimization of an Apoptosis Assay for Osteoblasts, Kyle Anderson 3rd Annual IWU Celebration of Scholarship: Apoptosis in Osteoblasts: Investigating a Potential Treatment for Osteoporosis, Jolie Hoffman, Kyle Anderson, Amber Jones 4th Annual IWU Celebration of Scholarship: Osteoblast Apoptosis Inducers: A Factor in Osteoporosis, Carolyn Bainbridge Colorimetric TUNEL Assays of MC3T3-E1 Osteoblasts: Visualizing Glucocorticoid Induced Apoptosis, Chana Hunter CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay, Amber Jones TGF-1 Levels in Dexamethasone-Induced Apoptotic Cells, Chris Rose Apoptosis Detection Through DNA Fragmentation, Michelle Stuttle Bcl-XL Levels in Apoptotic Osteoblasts: The Search for a Potential Role of Bcl-XL in Protecting Osteoblasts from Glucocorticoid-Induced Apoptosis During CD40 Ligand Signalling, Brittany Wilkerson DNA Isolation of Black-Capped, Carolina, and Hybrid Chickadee Blood, Jerica Derr 19th Annual Butler University Undergraduate Research Conference: CD40 Ligand Reversal of Dexamethasone-Induced Osteoblast Apoptosis as Measured by a Colorimetric Caspase-3 Assay, Amber Jones 122nd Indiana Academy of Science Fall Meeting: Successful Use of Guava Technologies’ Nexin Assay for Apoptosis Determination in MC3T3-E1 Cells, Carolyn Bainbridge Bcl-XL Levels in Apoptotic Osteoblasts: The Search for a Potential Role of Bcl-XL in Protecting Osteoblasts from Glucocorticoid-Induced Apoptosis During CD40 Ligand Signalling, Brittany Wilkerson Colorimetric TUNEL Assays of MC3T3-E1 Osteoblasts: Visualizing Glucocorticoid Induced Apoptosis, Chana Hunter TGF-1 Levels in Dexamethasone-Induced Apoptotic MC3T3-E1 Cells, Chris Rose Genomic DNA Isolation from Indiana Chickadee Species (Poecile sp.), Jerica Derr, Adam Thada 5th Annual IWU Celebration of Scholarship: Successful Use of Guava Technologies’ Nexin Assay for Apoptosis Determination in MC3T3-E1 Cells, Carolyn Bainbridge Bcl-XL Levels in Apoptotic Osteoblasts: The Search for a Potential Role of Bcl-XL in Protecting Osteoblasts from Glucocorticoid-Induced Apoptosis During CD40 Ligand Signalling, Brittany Wilkerson Colorimetric TUNEL Assays of MC3T3-E1 Osteoblasts: Visualizing Glucocorticoid Induced Apoptosis, Chana Hunter TGF-1 Levels in Dexamethasone-Induced Apoptotic MC3T3-E1 Cells, Chris Rose Does DNA Laddering Occur in the MC3T3-E1 Bone Tissue Culture Model Following Glucocorticoid-Induced Apoptosis? Jen Robinson Genomic DNA Isolation from Indiana Chickadee Species (Poecile sp.), Jerica Derr, Adam Thada 123rd Indiana Academy of Science Fall Meeting: The Role of Protein Kinase B in CD40 Ligand-Mediated Prevention of Glucocorticoid-Induced Osteoblast Apoptosis, Chika Nwulu A Preliminary Analysis of Nucleotide Differences Among Indiana Chickadee Species (Poecile sp.) at the Mitochondrial Cytochrome B Gene Locus, Brett Bishop Development of a Non-Radioisotopic Southern Blot Technique for Detecting Restriction Fragment Length Polymorphisms Among Indiana Chickadee Species (Poecile sp.) and Their Hybrids at the C7 Homology Locus, Matt Zuellig 6th Annual IWU Celebration of Scholarship: A Preliminary Analysis of Nucleotide Differences Among Indiana Chickadee Species (Poecile sp.) at the Mitochondrial Cytochrome B Gene Locus, Brett Bishop Development of a Non-Radioisotopic Southern Blot Technique Detecting Restriction Fragment Length Polymorphisms Among Indiana Chickadee Species and Their Hybrids at the Mitochondrial Cytochrome B Locus, Matt Zuellig The Role of TGF-1 in Osteoblasts in Glucocorticoid-Induced Osteoporosis, Kristen Shafer Apoptosis in Osteoblasts Treated with Dexamethasone and CD40 Ligand, Bethany Kline The Role of Protein Kinase B in CD40 Ligand-Mediated Prevention of Glucocorticoid-Induced Osteoblast Apoptosis, Chika Nwulu Dexamethasone-Induced Apoptosis can be Detected in MC3T3-E1 Mouse Osteoblasts using Promega Corporation’s Caspase-3 Activity Assay, Dan Seitz Effects of Estrogen on Osteoclast Apoptosis, Chris Sloan and Laura Tedeschi An Investigation of the In Vitro Induction of Osteoclast Apoptosis Related to the Treatment of Osteoporosis by Estrogen, Reveromycin A, and Orientin, Laura Tedeschi Apoptosis in Osteoblasts Treated with Dexamethasone and CD40 NF-B Inhibition and Osteoporosis, Brittany Mead The Role of Bcl-xL in the Apoptosis of Osteoblasts and The Validity of TRAP Staining for Interpreting Differentiation of RAW264.7 Cells by RANKL, Josh Pattengale The Signal Transduction Pathway of Tumor Necrosis Factor - as it Relates to Osteoclastogenesis, Jordan Mast 125th Annual Indiana Academy of Science Fall Meeting: Preliminary Investigation of Apoptosis Induction in Osteoclasts by the Flavonoid, Glucoluteolin, Heather Morgan Osteoporosis and Apoptosis, Megan Gragg The Role of IB in Reveromycin A-Induced Osteoclast Apoptosis, The Role of NF-B/IB in the Regulation of Osteoclast Survival, Use of an LDH Release Assay for Measuring Necrosis in Osteoclasts and Osteoblasts, Cory Hines Preliminary Investigation of Apoptosis in Osteoclasts by the Flavonoid, Glucoluteolin, Heather Morgan Characterization of Bone Cells in Osteoporosis: Use of the Bradford Assay in Cell Extract Protein Quantitation, Chris Devries Effect of Bcl-XL on Osteoclast Survival and Function, Spenser Lang MC3T3-E1 Cells Treated with the Bisphosphonate, Alendronate, Show Signs of Necrosis, Ben Kawsky The Role of Bcl-XL in the Regulation of Apoptosis in Bone Cells, 126th Annual Indiana Academy of Science Meeting, Oral Caspase 3 Activity Increases in Reveromycin A-Treated Reveromycin A-Induced Apoptosis in Osteoclasts is not Accompanied by Necrosis, Cory Hines Western Blot Analysis of Potential Mediators of Reveromycin A- Induced Apoptosis in Osteoclasts, Kaitlin Riemann 9th Annual Celebration of Scholarship, Natural Sciences Electrophoretic Mobility Shift Assay Control Tests to Confirm Binding of Protein to DNA, Emily Boyd and Tyler Derr Caspase 3 Activity Increases in Reveromycin A-Treated Reveromycin A-Induced Apoptosis in Osteoclasts is not Accompanied by Necrosis, Cory Hines Western Blot Analysis of Potential Mediators of Reveromycin A- Induced Apoptosis in Osteoclasts, Kaitlin Riemann The Effects of Reveromycin A on Healthy Equine Chondrocytes, 9th Annual Celebration of Scholarship, Natural Sciences Reveromycin A-Induced Apoptosis in Osteoclasts is not Accompanied by Necrosis, Cory Hines MC3T3-E1 Cells Treated with the Bisphosphonate, Alendronate, Show Signs of Necrosis, Ben Kawsky Western Blot Analysis of Potential Mediators of Reveromycin A- Induced Apoptosis in Osteoclasts, Kaitlin Riemann The Effects of Reveromycin A on Healthy Equine Chondrocytes, Characterization of the Mechanism of Reveromycin A-Induced Apoptosis in Osteoclasts, Jonathan Stofer Hodson Summer Research Institute Colloquium Presentations: Investigation of a Potential Bone-Preserving Agent for Osteoporosis Treatment, Reveromycin A, Tyler Derr (Power Point talk) and Jon 10th Annual Celebration of Scholarship, Natural Sciences Successful Western Blot Visualization of NFB and -actin Loading Control Signals from Osteoclasts, David Collins and Paul Landis Investigation of Reveromycin A-Induced Cell Death Effects in Chondrocytes, Lauren Nugent and Ryan Saba Successful Visualization of NFB-DNA Complex Formation: Using the Electrophoretic Mobility Shift Assay, Tyler Derr and Emily Boyd 10th Annual Celebration of Scholarship, Natural Sciences Optimization of NFB Western Blot Signal in Reveromycin A- Treated Osteoclasts, David Collins Optimization of a -actin Western Blot Loading Control in Reveromycin A-Treated Osteoclasts, Paul Landis Characterization of Cell Death Effects in Reveromycin A-Treated Mouse Chondrocytes, Lauren Nugent Optimization of the ATDC5 Mouse Chondrocyte Line for Studying Potential Reveromycin A-Induced Cell Death, Ryan Saba 13th Annual American Chemical Society, Indiana Chapter Meeting, Poster Presentation: Investigating the Effect of Reveromycin A, a Potential Osteoporosis Treatment, on Cartilage Cells of the Bone-Joint Microenvironment, Ellen Steinke Hodson Summer Research Institute Colloquium Presentations: Investigating the Effect of Reveromycin A, a Potential Osteoporosis Treatment, on Cartilage Cells of the Bone-Joint Microenvironment, Ellen Steinke, (Power Point talk and poster) 11th Annual Celebration of Scholarship, Oral Presentations: Reveromycin A Does Not Cause Apoptosis or Necrosis in the ATDC5 Chondrocyte Cell Line at Physiological pH, Kelsey Davitt Murine Chondrocytes do not Exhibit Significant Apoptosis when Treated with Reveromycin A as Measured by the TUNEL Assay, Investigation of a Mevalonate Pathway Metabolite for Rescue from Bisphosphonate-Related Osteonecrosis of the Jaw, Brooke Johnson (Awarded Outstanding Natural Sciences 11th Annual Celebration of Scholarship, Poster Presentations: Reveromycin A Does Not Cause Apoptosis or Necrosis in the ATDC5 Chondrocyte Cell Line at Physiological pH, Kelsey Davitt and Ellen Steinke Murine Chondrocytes do not Exhibit Significant Apoptosis when Treated with Reveromycin A as Measured by the TUNEL Assay, Emily Sloane and Ellen Steinke Investigation of a Mevalonate Pathway Metabolite for Rescue from Bisphosphonate-Related Osteonecrosis of the Jaw,
PROFESSIONAL MEMBERSHIP:
2003-
Cell Biology Section Co-Chair, 126th Annual Indiana Academy of Christian Medical & Dental Associations CONFERENCES AND WORKSHOPS:
2003
Attended IWU Teaching Workshops—Introduction to Blackboard Technology, Writing World Changing Outcomes, and Teaching Tips Attended CCCU National New Faculty Workshop Attended Indiana University School of Medicine Premedical Attended IWU Teaching Workshop—Faculty Guide to Helping Attended 12th Annual Conference on Bioethics—Genetic & Reproductive Ethics: The Scientific Cutting Edge & The Everyday Healthcare Challenges, Trinity International University Center for Bioethics and Human Dignity Attended Taylor University’s Technology for Teaching Conference Attended IWU Teaching Workshops—Are You Getting the IDEA? and Mentoring Attended NACADA (National Academic Advising Association) Academic Advising Summer Institute, Austin, Texas Attended Taylor University’s Technology for Teaching Conference Led an IWU Faculty Development Workshop: Workshop for Improving the Advising Experience at IWU Led an IWU Faculty Development Workshop: Advising the Wildcat Way Attended Indiana University School of Medicine Premedical Advisor’s Conference Attended IWU “The Pedagogy of Faith in the Science Classroom” Conference Attended the 2011 Global Missions Health Conference, Louisville, Kentucky, taking 25 IWU undergraduates IWU Center for Learning and Innovation, successful completion of Learning Academy 102: Assessment of Student Learning School of Physical and Applied Sciences Faculty Retreat—Pre-Med Advising Update Attended Indiana University School of Medicine Premedical Advisor’s Conference Attended the 2012 Global Missions Health Conference, Louisville, Kentucky, taking 11 IWU undergraduates
PUBLICATIONS:
Jones, D. and Leffak, M. A Negative Regulatory Element of the Human
Apolipoprotein A1 Gene, published abstract, The FASEB Journal, April 19, 1994,
8(7):A1335.
Jones, Daniel R. and Leffak, Michael. A Bifunctional Regulatory Element of the
Human ApoA-1 Gene Responsive to a Distal Enhancer. DNA & Cell Biology,
February 1999, 18(2):107-19.
Jones, D., Schmidt, R., Pickard, T., and Eacho, P. Dose-dependent Repression
of Hepatic Lipase Gene Transcription by 17 -estradiol, published abstract, The
FASEB Journal, May 11, 2000, 14(8):A1340.

Jones, Daniel R., Schmidt, Robert J., Pickard, Richard T., Foxworthy, Patricia
S., and Eacho, Patrick I. Estrogen Receptor-Mediated Repression of Human
Hepatic Lipase Gene Transcription, Journal of Lipid Research, 2002, 43:383-391.
Jones, D., Torrungruang, K., Selvamurugan, N., Partridge, N., and Bidwell, J.
Nmp4, a Nuclear Matrix Transcription Factor, Contributes to MMP-13
Transcription in Osteoblasts and Fibroblasts, published abstract, Molecular
Biology of the Cell, November 2001 Supplement, 12:496A.
Bidwell, J., Torrungruang, K., Alvarez, M., Rhodes, S., Shah, R., Jones, D.,
Charoonpatrapong, K., Hock, J., and Watt, A. Involvement of the Nuclear Matrix
in the Control of Skeletal Genes: The NMP1 (YY1), NMP2 (Cbfa1), and NMP4
(Nmp4/CIZ) Transcription Factors, Critical Reviews in Eukaryotic Gene
Expression, 2001, 11(4):279-298.
, , Nmp4/CIZ Regulation of Matrix Metalloproteinase 13 (MMP-13) Response to
Parathyroid Hormone in Osteoblasts, American Journal of Physiology—
Endocrinology & Metabolism, 2004, 287:289-296.
Jones, Daniel R. Biology 102 Lab Manual, August 2005.
Jones, Daniel R. Case Study: Using Microbe Molecular Biology for Gulf Oil Spill
Clean Up, Biochemistry and Molecular Biology Education, 2011, 39(2): 157-164.
Steinke, E. and Jones, D. Investigating the Effect of Reveromycin A, a Potential
Osteoporosis Treatment, on Cartilage Cells of the Bone-Joint Microenvironment,
13th Annual American Chemical Society Indiana Chapter Meeting Poster
Presentations Program, Fall 2012.
Mead, B., Morgan, H., Tedeschi, L., Hines, C., Lang, S., Jones, D. Reveromycin
A-Induced Apoptosis in Murine Osteoclasts Involves NFB Inactivation,
manuscript in preparation.

INVITED TEXT REVIEW/NATIONAL COMMITTEES:
2005
Chapter review of genetics text, The Logic of Genetics, for Benjamin Cummings Chapter review of genetics text, iGenetics, 2nd edition, for Benjamin Cummings American Chemical Society—2008 National Biochemistry Exam Committee Member, Contributor Chapter review of genetics laboratory text, Genetics Laboratory Investigations, 13th edition, for Pearson Prentice Hall
GRANTS:
2004
Full funding from Indiana Academy of Science for senior research project, An Investigation of the Anti-Apoptotic Mechanism of CD40 Ligand in Dexamethasone-Induced Osteoblast Apoptosis Mentored four individual students’ Lilly Student Research Award applications through IWU, two awarded Full funding of Lilly Faculty Scholarship grant application through IWU, A Study of the Mechanisms of Dexamethasone-Induced Apoptosis in Osteoblasts—An Important Piece in the Osteoporosis Puzzle Mentored three individual students’ Lilly Student Research Award applications, all awarded Successful funding of Lilly Faculty Scholarship grant application for summer research stipend Full funding for senior research scientist grant from the Indiana Academy of Science, Characterization of the Effect of Glucoluteolin, a Flavonoid, on Estrogen-Induced Apoptosis in Osteoclasts Mentored two individual students’ Lilly Student Research Award applications, both awarded Successful funding of Lilly Faculty Scholarship grant application for summer research stipend Successful funding of Lilly Faculty Scholarship grant application for summer research stipend Successful funding of IWU Hodson Summer Research Institute proposal Successful funding for Lilly Faculty Scholarship grant application Successful funding for Lilly Faculty Research Load Award Successful funding of IWU Hodson Summer Research Institute proposal Successful funding for Lilly Faculty Scholarship grant application Full funding for senior research scientist grant from the Indiana Academy of Science, Investigation of Reveromycin A-Induced Cell Death Effects in Chondrocytes Successful funding of IWU Hodson Summer Research Institute proposal
COMMUNITY SERVICE:
2000-
Coordinated my students’ efforts on Operation Christmas Child in conjunction with Lakeview Wesleyan Church, Marion, IN Push-pull and set-up team—Hamilton County Passion Play, Behold the Lamb, Noblesville, IN Usher—Hamilton County Passion Play, Behold the Lamb, Noblesville, IN 2006, 2007 ACSI District Science Fair judge 2009 Hamilton County Good Samaritan’s food delivery participant Habitat for Humanity Greater Indianapolis Volunteer Wheeler Lighthouse Men’s Emergency Center Indianapolis Volunteer
UNIVERSITY SERVICE:
2003-
Natural Sciences Division mentor for Barry Goldwater Scholarship Natural Sciences Division mentor for Elie Weisel Foundation Prize in Ethics Essay Contest candidates Member, Indiana Wesleyan University Institutional Review Board Faculty member, College of Arts and Sciences’ Academic Advising Committee Chairman, College of Arts and Sciences’ Academic Advising Committee Member, Scholarship Council—Lilly Student Awards Subcommittee Member, Scholarship Council—Chairman Lilly Faculty Awards Outstanding Teacher Subcommittee Member, IWU IACUC (Institutional Animal Care and Use Committee) Member, Scholarship Council—Chairman of Subcommittee for Lilly Faculty Research Awards (Load Release Awards) and Provost’s World Changing Faculty Award Faculty advisor for the IWU chapter of CMDA
CHURCH:
2002-04 Member, Grace Community Church, Noblesville, IN
2002-04
Participant, Community Group Bible Fellowship 2004- Member, Harbour Shores Church, Cicero, IN 2004- Participant, Ambassadors Adult Bible Study Fellowship 2004-05 2006-2009 Pathway to Maturity Bible Studies 2008-2009 Prayer in the Home leader/participant 2009-2012 Men’s Triple Cord Ministry 2010- Hamilton County Passion Play participant

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