Schulausbildung 09/80 - 06/88
naturwissenschaftliches Realgymnasium, 3500 Krems
Studium 10/88-03/99
Zoologie und Ökologie an der Universität Wien.
Präsenzdienst 04/97 - 11/97
Beruflicher Werdegang seit 1999
Wissenschaftlicher Mitarbeiter am Zentrum für Biomedizinische
Donau-Universität Krems, Leitung diverser
6 Wochen Forschungsaufenthalt am Institute for Biocybernetics and
Biomedical Engineering, Polish Academy of Science, Warschau.
Projekt “Tecnet AREA Biotechnologie” im Auftrag der NÖ
Leitung des Fachbereiches Verfahrenstechnik des Zentrums für
Biomedizinische Technologie der Donau-Universität Krems
Ausbildung zum QM-Beauftragten (QMS & QMSA) beim ÖVQ
Qualitätsbeauftragter des Zentrums für Biomedizinische Technologie der Donau-Universität Krems
Beauftragter der obersten Leitung der ISO-zertifizierten Bereiche der Abteilung für Klinische Medizin & Biotechnologie bzw. Department für Gesundheitswissenschaften und Biotechnologie, Donau-Universität Krems
Weitere Qualifikationen Fremdsprachen:
VBIO (Verband Biologie, Biowissenschaften und Biomedizin) ESAO (European Society for Artificial Organs) Diplomarbeit und Dissertation
J. Hartmann (1999): Wirkung von ß-Naphthoflavon als Substitut für ubiquitäre Umweltgifte an zwei Arten von Schmetterlingsraupen. Diplomarbeit. J Hartmann (2007): Procedureal Aspects in Extracorporeal Blood Purification. Dissertation. Peer Reviewed Publikationen
W. Strobl, I. Linsberger, J. Hartmann, G. Vogt, M. Schoenhofen, E. Sabrowski, F. Loth and D, Falkenhagen: FPSA-System: Effective in Continuous Removal of Protein bound and High Molecular Weight toxins From Blood. Proceeding of the EMBEC 99, Part I. D. Falkenhagen, W. Strobl, J. Hartmann, A. Schrefl, I. Linsberger, K-H. Kellner, F. Aussenegg, A. Leitner (2002): Patient Safety Technology for Microadsorbent Systems in Extracorporeal Blood Purification. Artif Organs, 26 (2): 84-90. M. Brandl, J. Hartmann, T. Posnicek, F. R. Aussenegg, A. Leitner, D. Falkenhagen (2005): Detection of Fluorescently Labeled Microparticles in Blood. Blood Purif, 23 (3), 181-189. J. Hartmann, C. Schildböck, M. Brandl, D. Falkenhagen (2005): Particle Leakage in Extracorporeal Blood Purification Systems Based on Microparticle Suspensions. Blood Purif, 23 (4): 282-286. Falkenhagen D., Brandl M., Hartmann J., Kellner K.H., Linsberger I., Posnicek T., and Weber V. (2006) Fluidized bed adsorbent systems for extracorporeal liver support. Ther Apher Dial, 10 (2): 154-159. M. Brandl, J. Hartmann, D. Falkenhagen (2006): New Methods for Haemoglobin Detection in a Microparticle - Plasma Suspension. Int J Artif Organs, 29 (11): 1092-1100. Weber V., Hartmann J., Linsberger I., and Falkenhagen D. (2007): Efficient adsorption of tumor necrosis factor with an in vitro set-up of the Microspheres-Based Detoxification System. Blood Purif, 25 (2),169-174. Hartmann J., Strobl K., Falkenhagen D. (2008): Anticoagulation in combined membrane/adsorption systems. Symposium: Artificial Organ - From in vitro assessment to human therapies. ISSN 0351-3254. Harm S, Strobl K, Hartmann J, Falkenhagen D: Alginate-Encapsulated Human Hepatoma C3A Cells for use in a Bioartificial Liver Device - the Hybrid-MDS. Int J Art Org, 32, 11, 2009.
Brandl M, Mayer M, Hartmann J, Posnicek T, Fabian C, Falkenhagen D: Theoretical Analysis of Ferromagnetic Microparticles in Streaming Liquid Under the Influence of External Magnetic Forces. J Magn Magn Mater, 322, 2454-2464, 2010. Brandl M, Strobl K, Hartmann J, Kellner K, Posnicek T, Falkenhagen D: A Target-Orientated Algorithm for Regional Citrate-Calcium Anticoagulation in Extracorporeal Therapies. Blood Purif 2012, 33, 7-20. Hartmann J, Strobl K, Fichtinger U, Schildböck C, Falkenhagen D (2012): In vitro investigations of citrate clearance with different dialysis filters. Int J Art Org 2012, May; 35(5): 352-9. Strobl K, Hartmann J, Wallner M, Brandl M, Falkenhagen D (2013). A target-oriented algorithm for citrate-calcium anticoagulation in clinical practice. Blood Purif. 2013;36(2):136-145.
Hartmann J, Beyer R, Harm S. Effective Removal of Estrogens from Drinking Water and Wastewater by Adsorption Technology. Environmental Processes Journal, 2014. Accepted for Publication.
Harm S, Falkenhagen D, Hartmann J. Endotoxin Adsorbents in Extracorporeal Blood Purification – Do They Fulfill The Expectations? Int J Art Org, 2014. Accepted for Publication.
Patente
M. Brandl, J. Hartmann, D. Falkenhagen (2004): Verfahren und Vorrichtung zur Detektion von markierten Mikropartikeln. Österreichische Patentanmeldung AZ 431/2004, Europäisches Patent EP 1 574 259 A1 (2005). Brandl M, Falkenhagen D, Hartmann J, Strobl K (2007): Verfahren zum Erfassen der Ionenkonzentration bei Citrat-Antikoagulierter Extrakorporaler Blutreinigung. Österreichische Patentanmeldung A 1368/2007. Europäisches Patent EP2200675 A1 30.06.2010. Falkenhagen D, Hartmann J, Weber V (2010): Sorptionsmittel zum Entfernen proteingebundener Substanzen./Sorbent for Removing Protein-Bound Substances. Patentanmeldung PCT/AT2010/000016. WO Patent WO/2010/083,544. EP Patent 2,389,206. US Patent 2012/0125857 A1. Falkenhagen D, Harm S, Hartmann J, Weber V (2010): Neuartiges Sorptionsmittel für Endotoxine./Novel Sorbent for Endotoxins. Österreichisches Patent A-1073/2010, Internationale Patentanmeldung PCT/AT2011/000273, 29.12.2011. WO Patent WO/2011/160149. Brandl M, Falkenhagen D, Hartmann J: Sicherheitseinrichtung für eine extrakorporale Blutbehandlung. Europäische Patentanmeldung 12164284.7-1257. 10.04.2012. Falkenhagen D, Harm S, Hartmann J (2012): Selektives Sorptionsmittel für die extrakoprporale Blutreinuigung. Europäische Patentanmeldung 12174028.6-1257, 28.06.2012. Falkenhagen D, Harm S, Hartmann J (2012): Dosierungsanleitung für endotoxinbindende Lipopeptide. Europäische Patentanmeldung 12174285.2-2123, 29.06.2012.
Falkenhagen D, Harm S, Hartmann J: Extrakorporale Perfusionseinrichtung. Europäische Patenteinreichung Nr. 12174028.
Tagungsbände (Proceedings) D. Schwanzer-Pfeiffer, A. Ciechanowska, A. Józwiak, J. Hartmann, S. Sabalinska, D. Falkenhagen, J. Wójcicki (2002): Hodowla komòrek sródblonka na polisulfonowych membranach pólprzepuszczalnych plaskich i kapilarnych. XII Krajowa Konferencja Naukowa Biocybernetyka i Inzynieria Biomedyczna. (Proceedings of the XII conference of Biocybernetics and Biomedical Engineering). Warsaw, 2002. ISBN 83-901334-5-8. A. Ciechanowska, S. Sabalinska, C. Wojciechowski, A. Jozwiak, E. Rossmanith, J. Hartmann, K. Hellevuo, D. Falkenhagen, J.M. Wojcicki (2003): A Capillary Bioreactor with Endothelial Cells – Peliminary Study. Proceedings of 13th National Scientific Conference on Biocybernetic and Biomedical Engineering. Gdansk, Sept 10-13, 2003, 139-144. Ciechanowska, D. Schwanzer-Pfeiffer, E. Rossmanith, S. Sabalinska, C. Wojciechowski, J. Hartmann, K. Hellevuo, A. Chwojnowski, P. Foltynski, D. Falkenhagen, J. Wojcicki (2004): Artificial Vessel as a Basis for Disease Related Cell Culture Model. IFMBE Proceedings, 6, 2004. M. Brandl, K. Kellner, K. Strobl, J. Hartmann, T. Posnicek, D. Falkenhagen: An Optimized Algorithm for Regional Citrate-Calcium Anticoagulation. Proceedings ICMIBE 2010, International Conference on Medical Informatics and Biomedical Engineering, Rio de Janeiro, Brazil, March 29-31, 2010, pp. 494. Bücher und Buchbeiträge
D. Falkenhagen, W. Strobl, A. Schrefl, J. Hartmann, F. Aussenegg, A. Leitner, A. Krause, M. Schoenhofen (2000): Alternative Behandlungsmöglichkeiten für die extrakorporale Blutreinigung. In: Extrakorporaler Blutkreislauf und Dialyse - Symbiose von Medizin und Technik, S. 163-174, Pabst Verlag. D. Falkenhagen, W. Strobl, A. Schrefl, J. Hartmann, F. Aussenegg, A. Leitner, M. Schoenhofen (2001): Neue Adsorptionstechnologien für die extrakorporale Blutreinigung. Medizin 2001, Aus Forschung und Praxis. Dr. Peter Müller Verlag, Wien. ISBN 3-900784-21-3 Abstracts und Posterpräsentationen
D. Falkenhagen, W. Strobl, J. Hartmann, A. Schrefl, I. Linsberger, F. Aussenegg, A. Leitner: Patient safety technology for microspheres adsorbent suspension technologies; ASAIO-Journal 46, 2, 214, 2000 (abstract). Poster presentation ASAIO 2000. J. Hartmann, A. Schrefl, W. Strobl, Ingrid Linsberger, K.-H. Kellner, F. Aussenegg, A. Leitner and D. Falkenhagen (2000): Membrane Leakage detection based on microparticles marked with fluorescent dyes. Int. J. of Art. Organs, 23 (8). Abstract. Poster presentation ESAO 2000.
W. Strobl, I. Linsberger, J. Hartmann, E. Sabrowski, D. Falkenhagen (2000): Decreasing particle size improves Adsorption in Extracorporeal Blood Purification. Polymers in Medicine and Surgery (PIMS), IOM Communications Ltd., S. 447-453. ISBN 1-86125-126-2. A. Schrefl, K.H. Kellner, J. Hartmann, W. Strobl, D. Falkenhagen (2001): A Novel Monitor for Anticoagulation with Citrate. Int. Journ. Artif. Organs 24 (8), 535 (abstract). W. Strobl, J. Hartmann, I. Linsberger, D. Pfeiffer, V. Weber, D. Falkenhagen (2001): Comparison of Membrane/Adsorbent-based Blood Purification Devices in Liver Failure in vitro. Int. Journ. Artif. Organs 24 (8), 556. A. Ciechanowska, D. Schwanzer-Pfeiffer, E. Rossmanith, S. Sabalinska, C. Wojciechowski, J. Hartmann, K. Hellevuo, A. Chwojnowski, P. Foltynski, D. Falkenhagen, J.M. Wojcicki (2004): Artificial Vessel as a basis for Disease Related Cell Culture Model. Medicon 2004, Neapel, Italien. Abstract. E. Rossmanith, A. Ciechanowska, S. Sabalinska, D. Schwanzer-Pfeiffer, C. Wojciechowski, J. Hartmann, K. Hellevuo, A. Chwojnowski, P. Foltynski, D. Falkenhagen, J.M. Wojcicki (2004): Development of an Endothelian Cell Culture Model for Studies on Vascular Pathophysiology in Sepsis. ESAO congress 2004, Warschau, Polen. Abstract. M. Brandl, T. Posnicek, J. Hartmann, D. Falkenhagen (2003): Flowdynamic Microparticle Separation for Extracorporeal Haemofiltration Systems. ESAO congress 2003, Abstract. V. Weber, J. Hartmann, I. Linsberger, C. Schildböck, F. Loth, D. Falkenhagen (2005): Development of Specific Microadsorbents for Pathophysiological Mediators of Sepsis and Multi-Organ Failure. ISFA congress 2005, Abstract. J. Hartmann, K. Strobl, U. Fichtinger, D. Falkenhagen (2006): Citrate anticoagulation and activation of the complement system. ESAO congress 2006, Umea, Sweden. Abstract. Falkenhagen D., Hartmann J., Weber V. (2009): Importance of Nanostructured Pore-Size Distribution for Selected Adsorption-Therapy of Sepsis and Acute Liver Failure. BioNanoMed, Krems, Abstract. Brandl M, Hartmann J, Posnicek T, Falkenhagen D: Safety Analysis of a Microparticle-Based Detoxification System in case of a Filter Rupture. Int J Art Org, 32, 7, 2009, 444. Abstract and poster presentation. Strobl K, Hartmann J, Brandl M, Falkenhagen D: Preclinical Test of a Newly Developed Citrate Calcium Monitor. Int J Art Org, 32, 7, 2009, 438. Abstract and poster presentation. Hartmann J, Strobl K, Fichtinger U, Falkenhagen D: Influence of Mg2+ Concentration on the Suppression of the Complement System by Citrate. Int J Art Org, 32, 7, 2009, 438. Abstract and poster presentation. Falkenhagen D., Hartmann J., Weber V.: Nano-structured Polymer Based Microparticles for Extracorporal Blood Purification in the Treatment of Sepsis and Liver Failure. EPF European Polymer Congress 2009, Graz, July 12-17. Falkenhagen D., Harm S., Hartmann J., Springler A., Schwanzer-Pfeiffer D., Weber V.: The Hybrid MDS (Micropheres-based Detoxification System) - A future Perspective Extracorporal
Cell Therapy in Sepsis and Liver Failure. World Conference on regenerative Medicine (WRM), Leipzig, Oct 29-31, 2009. M. Brandl, K. Kellner, K. Strobl, J. Hartmann, T. Posnicek, D. Falkenhagen: An Optimized Algorithm for Regional Citrate-Calcium Anticoagulation. Proceedings ICMIBE 2010, International Conference on Medical Informatics and Biomedical Engineering, Rio de Janeiro, Brazil,March 29-31, 2010, pp. 494. Hartmann J, Fichtinger U, Falkenhagen D: Adaptation of a citrate test kit from the food industry for its application in blood and plasma analysis. ESAO Congress 2010, Skopje. Abstract and Poster Presentation. Falkenhagen D, Thijssen S, Brandl M, Harmann J, Strobl K. Relationship between Ionized Calcium Concentration and Activated Clotting Time in Citrate Anticoagulated Blood. J Am Soc Nephrol, 21:2010. Abstract and Poster Presentation. F. Simonis, C. Kotsokalis, J. Boomker, L. Pielawa, M. Brell, F. Poppen, M. Simonis, S. Wiegersma, A. Boersma, M. Ivan, A. Raptopoulos, M. Correvon, G. Dudnik, M. Schneider, H. Anis, F. Meyering, J. Fils, G. Marchand, J. Hartmann, M. Wester, J. Joles: Nephron+ wearable artificial kidney. ESAO 2011, Porto, Portugal. Abstract. Falkenhagen D, Brandl M, Hartmann J, Strobl K, Wallner M: Das Ionisierte Kalzium (iCA) als essenzielles Target für die Zitratantikoagulation (ZA). Intensivmedizin und Notfallmedizin, 48, 4, 362, 2011. Abstract/Poster. Falkenhagen D, Thijssen S, Brandl M, Hartmann J, Strobl K, Wallner M: No Change in Correlation Between ACT (Activated Clotting Time) and iCa (Ionized Calcium)-Concentration Comparing Blood of RDT-Patients and Healthy Donors. EDTA, Prag, 2011. Abstract/Poster.
Hartmann J, Beyer R, Harm S: Effective Removal of Estrogens from Drinking Water and Waste Water by Adsorption Technology. 8th International Conference of EWRA, Porto 2013 Poster Presentation.
Harm S, Beyer R, Hartmann J: A New and Simple Method for Simultaneous Detection of Native and Synthetic Estrogen. 8th International Conference of EWRA, Porto 2013. Poster Presentation.
Invited Lectures
J. Hartmann, M. Brandl, F. Loth, V. Weber, C. Schildböck, M. Ettenauer, D. Falkenhagen (2005): A Novel Device for Highly Sensitive Leakage Detection for Microparticle Suspension Based Blood Purification Systems. ISFA congress 2005, Abstract (Vortrag). Hartmann J., Strobl K., Falkenhagen D. (2007): Anticoagulation in combined membrane/adsorption systems. Symposium: Artificial Organ - From in vitro assessment to human therapies. Skopje, Macedonia. Hartmann J.: Targeting Ionized Calcium - An Essential Tool in Citrate Anticoagulation. 4th joint ESAO-IFAO Congress, Oct 09-12 2011, Porto, Portugal.
Hartmann J.: Endotoxin removal in blood purification – a big challenge. One Day on the Liver. Artificial Liver Support: An Update and Future Developments. ESAO supported Meeting. 9th of May 2012, Danube University Krems, Austria. Vorträge
J. Hartmann, M. Brandl, F. Loth, C. Kendl, D. Falkenhagen (2004): Microparticles in Extracorporeal Blood Purification – A Novel Device for Highly Sensitive Leakage Detection. ESAO 2004, Warschau, Polen. Hartmann J, Smeets JMW, de Zwart MAH, Peters SMA (2006): In vitro dialysability of sugammadex, a selective relaxant binding agent for reversal of neuromuscular block induced by rocuronium. ESA congress 2006, Madrid. Abstract, Poster & Vortrag. Hartmann J (2008): In vitro citrate clearance in dialysis. ESAO congress 2008, Geneva, Swizerland. Lecture and Abstract. Der Zitrat Kalzium Monitor. Vortrag im Rahmen des Hämofiltrationsseminars, Bad Ischl, 2010. Hartmann J, Fichtinger U, Schildböck C, Falkenhagen D: Improving the Biocompatibility of Adsorbents for Extracorporeal Blood Purification by Albumin Coating. ESAO Congress 2010, Skopje. Abstract and oral presentation. Betreute Arbeiten
Konzeption einer modernen Akutaufnahme anhand des Beispiels Barmherzige Kreuzschwestern in Wels - Vom Ideal zur Realität. Masterthese zur Erlangung des akademischen Grades Master of Business Administration im Rahmen des Executive MBA Programms, Donau-Universität Krems, 2008. Zweitgutachter. How to Optimize Marketing and Sales Activities in The Case of Launching the Drug Circadin®. Masterthese zur Erlangung des akademischen Grades Master of Business Administration im Rahmen des Professional MBA Biotech & Pharmaceutical Management Programms, Donau- Universität Krems, 2008. Zweitgutachter. Gruber A (2013): Adsorption of Selected Antibiotics to Resins in Extracorporeal Blood Purification. Master Thesis within the Master-Programme Medical and Pharmaceutical Biotechnology, University of Applied Sciences, Krems, Austria. Sonstige Publikationen und Veröffentlichungen
Fashion Show am Riff. Tauchen, Juni 2010, 62-71. Modeshow. Duiken, Juni 2010, 46-55.
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Int Urogynecol JDOI 10.1007/s00192-010-1294-yLong-term results of intravesical hyaluronan therapyin bladder pain syndrome/interstitial cystitisPaul F. Engelhardt & Nike Morakis & Lukas K. Daha &Britta Esterbauer & Claus R. RiedlReceived: 2 August 2010 / Accepted: 20 September 2010# The International Urogynecological Association 2010Introduction and hypothesis While the short