Farmacia italiana online: acquisto cialis in Italia e Roma senza ricetta.

Univ-montp1.fr

Vincent Cavaillès
Signalisation hormonale environnement et cancer
Linares A, Dalenc F, Balaguer P, Boulle N, Cavailles V. 2011. Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies? J Biomed Biotechnol 2011: 856985 Chambon M, Orsetti B, Berthe ML, Bascoul-Mollevi C, Rodriguez C, Duong V, Gleizes M, Thenot S, Bibeau F, Theillet C, Cavailles V. 2011. Prognostic Significance of TRIM24/TIF-1alpha Gene Expression in Breast Cancer. Am J Pathol 178: 1461-9 Teyssier C, Le Romancer M, Sentis S, Jalaguier S, Corbo L, Cavailles V. 2010. Protein arginine methylation in estrogen signaling and estrogen-related cancers. Trends Endocrinol Metab 21: 181-9 Savatier J, Jalaguier S, Ferguson ML, Cavailles V, Royer CA. 2010. Estrogen receptor interactions and dynamics monitored in live cells by fluorescence cross-correlation spectroscopy. Biochemistry 49: 772-81 Docquier A, Harmand PO, Fritsch S, Chanrion M, Darbon JM, Cavailles V. 2010. The Transcriptional Coregulator RIP140 Represses E2F1 Activity and Discriminates Breast Cancer Subtypes. Clin Cancer Res 16: 2959-70 Sassi-Messai S, Gibert Y, Bernard L, Nishio S, Ferri Lagneau KF, Molina J, Andersson-Lendahl M, Benoit G, Balaguer P, Laudet V. 2009. The phytoestrogen genistein affects zebrafish development through two different pathways. PLoS ONE 4: e4935 le Maire A, Grimaldi M, Roecklin D, Dagnino S, Vivat-Hannah V, Balaguer P, Bourguet W. 2009. Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors. EMBO Rep 10: 367-73 Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
Garrel R, Raynaud P, Raingeard I, Muyshondt C, Gardiner Q, Guerrier B, Pujol P, Coupier I. 2009. An unusual succinate dehydrogenase gene mutation C in a case of laryngeal paraganglioma. J Laryngol Otol 123: 141-4 Escande A, Servant N, Rabenoelina F, Auzou G, Kloosterboer H, Cavailles V, Balaguer P, Maudelonde T. 2009. Regulation of activities of steroid hormone receptors by tibolone and its primary metabolites. J Steroid Biochem Mol Biol 116: 8-14 Dupasquier S, Abdel-Samad R, Glazer RI, Bastide P, Jay P, Joubert D, Cavailles V, Blache P, Quittau-Prevostel C. 2009. A new mechanism of SOX9 action to regulate PKCalpha expression in the intestine epithelium. J Cell Sci 122: 2191-6 Badia E, Escande A, Balaguer P, Metivier R, Cavailles V. 2009. New stably transfected bioluminescent cells expressing FLAG epitope-tagged estrogen receptors to study their chromatin recruitment. BMC Biotechnol 9: 77 Truchet I, Jozan S, Baron S, Frongia C, Balaguer P, Richard-Foy H, Valette A. 2008. Estrogen and antiestrogen-dependent regulation of breast cancer cell proliferation in multicellular spheroids: Influence of cell microenvironment. Int J Oncol 32: 1033-9 Scott RH, Douglas J, Baskcomb L, Huxter N, Barker K, Hanks S, Craft A, Gerrard M, Kohler JA, Levitt GA, Picton S, Pizer B, Ronghe MD, Williams D, Cook JA, Pujol P, Maher ER, Birch JM, Stiller CA, Pritchard-Jones K, Rahman N. 2008. Constitutional 11p15 abnormalities, including heritable imprinting center mutations, cause nonsyndromic Wilms tumor. Nat Genet 40: 1329-34 Ruegg J, Swedenborg E, Wahlstrom D, Escande A, Balaguer P, Pettersson K, Pongratz I. 2008. The Transcription Factor Aryl Hydrocarbon Receptor Nuclear Translocator Functions as an Estrogen Receptor {beta}-Selective Coactivator, and Its Recruitment to Alternative Pathways Mediates Antiestrogenic Effects of Dioxin. Mol Endocrinol 22: 304-16 Riu A, Balaguer P, Perdu E, Pandelova M, Piccinelli R, Gustafsson JA, Leclercq C, Schramm KW, Dagnino S, Debrauwer L, Cravedi JP, Zalko D. 2008. Characterisation of bioactive compounds in infant formulas using immobilised recombinant estrogen receptor-alpha affinity columns. Food Chem Toxicol 46: 3268-78 Muller M, Rabenoelina F, Balaguer P, Patureau D, Lemenach K, Budzinski H, Barcelo D, Lopez de Alda M, Kuster M, Delgenes JP, Hernandez-Raquet G. 2008. Chemical and biological analysis of endocrine-disrupting hormones and estrogenic activity in an advanced sewage treatment plant. Environ Toxicol Chem 27: 1649-58 Molina-Molina JM, Escande A, Pillon A, Gomez E, Pakdel F, Cavailles V, Olea N, Ait-Aissa S, Balaguer P. 2008. Profiling of benzophenone derivatives using fish and human estrogen receptor-specific in vitro bioassays. Toxicol Appl Pharmacol 232: 384-95 Lesueur F, de Lichy M, Barrois M, Durand G, Bombled J, Avril MF, Chompret A, Boitier F, Lenoir GM, Bressac-de Paillerets B, Baccard M, Bachollet B, Berthet P, Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
Bonadona V, Bonnetblanc JM, Caron O, Chevrant-Breton J, Cuny JF, Dalle S, Delaunay M, Demange L, De Quatrebarbes J, Dore JF, Frenay M, Fricker JP, Gauthier-Villars M, Gesta P, Giraud S, Gorry P, Grange F, Green A, Huiart L, Janin N, Joly P, Kerob D, Lasset C, Leroux D, Limacher JM, Longy M, Mansard S, Marrou K, Martin-Denavit T, Mateus C, Maubec E, Olivier-Faivre L, Orlandini V, Pujol P, Sassolas B, Stoppa-Lyonnet D, Thomas L, Vabres P, Venat L, Wierzbicka E, Zattara H. 2008. The contribution of large genomic deletions at the CDKN2A locus to the burden of familial melanoma. Br J Cancer 99: 364-70 Duong V, Bret C, Altucci L, Mai A, Duraffourd C, Loubersac J, Harmand PO, Bonnet S, Valente S, Maudelonde T, Cavailles V, Boulle N. 2008. Specific activity of class II histone deacetylases in human breast cancer cells. Mol Cancer Res 6: 1908-19 Buteau-Lozano H, Velasco G, Cristofari M, Balaguer P, Perrot-Applanat M. 2008. Xenoestrogens modulate vascular endothelial growth factor secretion in breast cancer cells through an estrogen receptor-dependent mechanism. J Endocrinol 196: 399-412 Benod C, Subra G, Nahoum V, Mallavialle A, Guichou JF, Milhau J, Robles S, Bourguet W, Pascussi JM, Balaguer P, Chavanieu A. 2008. N-1H-benzimidazol-5-ylbenzenesulfonamide derivatives as potent hPXR agonists. Bioorg Med Chem 16: 3537-49 Dany Chalbos
Contrôle de la progression des cancers hormono-dépendants
Freiss G, Chalbos D. 2011. PTPN13/PTPL1: An Important Regulator of Tumor Aggressiveness. Anticancer Agents Med Chem 11: 78-88 Nirde P, Derocq D, Maynadier M, Chambon M, Basile I, Gary-Bobo M, Garcia M. 2010. Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells. Oncogene 29: 117-27 Glondu-Lassis M, Dromard M, Lacroix-Triki M, Nirde P, Puech C, Knani D, Chalbos D, Freiss G. 2010. PTPL1/PTPN13 Regulates Breast Cancer Cell Aggressiveness through Direct Inactivation of Src Kinase. Cancer Res 70: 5116-26 Wang X, Belguise K, O'Neill CF, Sanchez-Morgan N, Romagnoli M, Eddy SF, Mineva ND, Yu Z, Min C, Trinkaus-Randall V, Chalbos D, Sonenshein GE. 2009. RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1. Mol Cell Biol 29: 3832-44 Revillion F, Puech C, Rabenoelina F, Chalbos D, Peyrat JP, Freiss G. 2009. Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer. Int J Cancer 124: 638-43 Ndlovu N, Van Lint C, Van Wesemael K, Callebert P, Chalbos D, Haegeman G, Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
Vanden Berghe W. 2009. Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells. Mol Cell Biol 29: 5488-504 Maynadier M, Basile I, Gary-Bobo M. 2009. Adiponectin normalization: a clue to the anti-metabolic syndrome action of rimonabant. Drug Discov Today 14: 192-7 Glondu-Lassis M, Dromard M, Chavey C, Puech C, Fajas L, Hendriks W, Freiss G. 2009. Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis. Int J Biochem Cell Biol 41: 2173-80 Faruque OM, Le-Nguyen D, Lajoix AD, Vives E, Petit P, Bataille D, Hani el H. 2009. Cell-permeable peptide-based disruption of endogenous PKA-AKAP complexes: a tool for studying the molecular roles of AKAP-mediated PKA subcellular anchoring. Am J Physiol Cell Physiol 296: C306-16 Brevet D, Gary-Bobo M, Raehm L, Richeter S, Hocine O, Amro K, Loock B, Couleaud P, Frochot C, Morere A, Maillard P, Garcia M, Durand JO. 2009. Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy. Chem Commun (Camb): 1475-7 Maynadier M, Ramirez JM, Cathiard AM, Platet N, Gras D, Gleizes M, Sheikh MS, Nirde P, Garcia M. 2008. Unliganded estrogen receptor {alpha} inhibits breast cancer cell growth through interaction with a cyclin-dependent kinase inhibitor (p21WAF1). In Faseb J, pp. 671-81 Maynadier M, Nirde P, Ramirez JM, Cathiard AM, Platet N, Chambon M, Garcia M. 2008. Role of estrogens and their receptors in adhesion and invasiveness of breast cancer cells. Adv Exp Med Biol 617: 485-91 Jeanjean A, Gary-Bobo M, Nirde P, Leiris S, Garcia M, Morere A. 2008. Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting. Bioorg Med Chem Lett 18: 6240-3 Gary-Bobo M, Maynadier M. 2008. Adiponectin normalization: a clue to the antimetabolic syndrome action of rimonabant. Drug Discov Today Lluis Fajas
Métabolisme et Cancer
___________________________________________________________________ Lagarrigue S, Blanchet E, Annicotte JS, Fajas L. 2011. [Emerging key role of cell cycle regulators in cell metabolism.]. Med Sci (Paris) 27: 508-13 Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
Fritz V, Fajas L. 2010. Metabolism and proliferation share common regulatory pathways in cancer cells. Oncogene 29: 4369-77 Fritz V, Benfodda Z, Rodier G, Henriquet C, Iborra F, Avances C, Allory Y, de la Taille A, Culine S, Blancou H, Cristol JP, Michel F, Sardet C, Fajas L. 2010. Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice. Mol Cancer Ther 9: 1740-54 Fajas L, Blanchet E, Annicotte JS. 2010. The CDK4-pRB-E2F1 pathway : A new modulator of insulin secretion. Islets 2: 51-3 Fajas L, Blanchet E, Annicotte JS. 2010. CDK4, pRB and E2F1: connected to insulin. Cell Div 5: 6 Aguilar V, Fajas L. 2010. Cycling through metabolism. EMBO Mol Med 2: 338-48 Aguilar V, Annicotte JS, Escote X, Vendrell J, Langin D, Fajas L. 2010. Cyclin G2 Regulates Adipogenesis through PPAR{gamma} Coactivation. Endocrinology 151: 5247-54 Clape C, Fritz V, Henriquet C, Apparailly F, Fernandez PL, Iborra F, Avances C, Villalba M, Culine S, Fajas L. 2009. miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice. PLoS One 4: e7542 Chavey C, Lazennec G, Lagarrigue S, Clape C, Iankova I, Teyssier J, Annicotte JS, Schmidt J, Mataki C, Yamamoto H, Sanches R, Guma A, Stich V, Vitkova M, Jardin-Watelet B, Renard E, Strieter R, Tuthill A, Hotamisligil GS, Vidal-Puig A, Zorzano A, Langin D, Fajas L. 2009. CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. Cell Metab 9: 339-49 Chavey C, Fajas L. 2009. CXCL5 drives obesity to diabetes, and further. Aging (Albany NY) 1: 674-7 Botton T, Puissant A, Bahadoran P, Annicotte JS, Fajas L, Ortonne JP, Gozzerino G, Zamoum T, Tartare-Deckert S, Bertolotto C, Ballotti R, Rocchi S. 2009. In Vitro and In Vivo Anti-Melanoma Effects of Ciglitazone. J Invest Dermatol Blanchet E, Annicotte JS, Fajas L. 2009. Cell cycle regulators in the control of metabolism. Cell Cycle 8: 4029-31 Annicotte JS, Blanchet E, Chavey C, Iankova I, Costes S, Assou S, Teyssier J, Dalle S, Sardet C, Fajas L. 2009. The CDK4-pRB-E2F1 pathway controls insulin secretion. Nat Cell Biol 11: 1017-23 Iankova I, Chavey C, Clape C, Colomer C, Guerineau NC, Grillet N, Brunet JF, Annicotte JS, Fajas L. 2008. RGS4 controls fatty acid and glucose homeostasis. Endocrinology 149: 5706-12 Mazzucotelli A, Viguerie N, Tiraby C, Annicotte JS, Mairal A, Klimcakova E, Lepin E, Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
Delmar P, Dejean S, Tavernier G, Lefort C, Hidalgo J, Pineau T, Fajas L, Clement K, Langin D. 2007. The Transcriptional Coactivator PGC-1{alpha} and the Nuclear Receptor PPAR{alpha} Control the Expression of Glycerol Kinase and Metabolism Genes Independently of PPAR{gamma} Activation in Human White Adipocytes. Diabetes 56: 2467-75 Emma Liaudet-Coopman
Cathepsines, Autophagie et Cancer
Masson O, Prebois C, Derocq D, Meulle A, Dray C, Daviaud D, Quilliot D, Valet P, Muller C, Liaudet-Coopman E. 2011. Cathepsin-d, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis. PLoS One 6: e16452 Masson O, Bach AS, Derocq D, Prebois C, Laurent-Matha V, Pattingre S, Liaudet-Coopman E. 2010. Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity? Biochimie 92: 1635-43 Beaujouin M, Prebois C, Derocq D, Laurent-Matha V, Masson O, Pattingre S, Coopman P, Bettache N, Grossfield J, Hollingsworth RE, Zhang H, Yao Z, Hyman BT, van der Geer P, Smith GK, Liaudet-Coopman E. 2010. Pro-cathepsin D interacts with the extracellular domain of the {beta} chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth. J Cell Sci 123: 3336-46 Pattingre S, Bauvy C, Levade T, Levine B, Codogno P. 2009. Ceramide-induced autophagy: to junk or to protect cells? Autophagy 5: 558-60 Pattingre S, Bauvy C, Carpentier S, Levade T, Levine B, Codogno P. 2009. Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. J Biol Chem 284: 2719-28 Masson O, Chavey C, Dray C, Meulle A, Daviaud D, Quilliot D, Muller C, Valet P, Liaudet-Coopman E. 2009. LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue. PLoS One 4: e7422 Berndtsson M, Beaujouin M, Rickardson L, Havelka AM, Larsson R, Westman J, Liaudet-Coopman E, Linder S. 2009. Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin-proteasome system. Int J Cancer 124: 1463-9 Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. 2008. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 30: 678-88 Pattingre S, Espert L, Biard-Piechaczyk M, Codogno P. 2008. Regulation of macroautophagy by mTOR and Beclin 1 complexes. Biochimie 90: 313-23 Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
Beaujouin M, Liaudet-Coopman E. 2008. Cathepsin D overexpressed by cancer cells can enhance apoptosis-dependent chemo-sensitivity independently of its catalytic activity. Adv Exp Med Biol 617: 453-61 Laurent Le Cam
Equipe Avenir
Bases Moléculaires de la Cancérogenèse
Lacroix M, Caramel J, Goguet-Rubio P, Linares LK, Estrach S, Hatchi E, Rodier G, Lledo G, de Bettignies C, Thepot A, Deraison C, Chebli K, Hovnanian A, Hainaut P, Dubus P, Sardet C, Le Cam L. 2010. Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis. Proc Natl Acad Sci U S A 107: 21076-81 Pierre Martineau
Bases moléculaires de la résistance aux traitements anti-tumoraux
___________________________________________________________________________ Paillas S, Boissiere F, Bibeau F, Denouel A, Mollevi C, Causse A, Denis V, Vezzio-Vie N, Marzi L, Cortijo C, Ait-Arsa I, Askari N, Pourquier P, Martineau P, Del Rio M, Gongora C. 2011. Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma. Cancer Res 71: 1041-9 Estephan E, Saab MB, Martin M, Larroque C, Cuisinier FJ, Briot O, Ruffenach S, Moret M, Gergely C. 2011. Phages recognizing the Indium Nitride semiconductor surface via their peptides. J Pept Sci 17: 143-7 Gongora C, Vezzio-Vie N, Tuduri S, Denis V, Causse A, Auzanneau C, Collod-Beroud G, Coquelle A, Pasero P, Pourquier P, Martineau P, Del Rio M. 2011. New Topoisomerase I mutations are associated with resistance to camptothecin. Mol Cancer 10: 64 Thierry AR, Mouliere F, Gongora C, Ollier J, Robert B, Ychou M, Del Rio M, Molina F. 2010. Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts. Nucleic Acids Res 38: 6159-75 Rogowski K, van Dijk J, Magiera MM, Bosc C, Deloulme JC, Bosson A, Peris L, Gold ND, Lacroix B, Grau MB, Bec N, Larroque C, Desagher S, Holzer M, Andrieux A, Moutin MJ, Janke C. 2010. A family of protein-deglutamylating enzymes associated with neurodegeneration. Cell 143: 564-78 Paillas S, Boissiere F, Bibeau F, Denouel A, Mollevi C, Causse A, Denis V, Vezzio- Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
Vie N, Marzi L, Cortijo C, Ait-Arsa I, Askari N, Pourquier P, Martineau P, Del Rio M, Gongora C. 2010. Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma. Cancer Res 71: 1041-9 Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, Bibeau F, Boissiere-Michot F, Thezenas S, Cellier D, Azria D, Rouanet P, Senesse P, Ychou M, Lopez-Crapez E. 2010. A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer. Pharmacogenomics J Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, Bibeau F, Boissiere-Michot F, Cellier D, Azria D, Rouanet P, Senesse P, Ychou M, Lopez-Crapez E. 2010. EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer. Int J Cancer Estephan E, Saab MB, Martin M, Larroque C, Cuisinier FJ, Briot O, Ruffenach S, Moret M, Gergely C. 2010. Phages recognizing the Indium Nitride semiconductor surface via their peptides. J Pept Sci. 17: 143-7 Bouslimani A, Bec N, Glueckmann M, Hirtz C, Larroque C. 2010. Matrix-assisted laser desorption/ionization imaging mass spectrometry of oxaliplatin derivatives in heated intraoperative chemotherapy (HIPEC)-like treated rat kidney. Rapid Commun Mass Spectrom 24: 415-21 Bonfils C, Bec N, Larroque C, Rio MD, Gongora C, Pugniere M, Martineau P. 2010. Cyclophilin A as negative regulator of apoptosis by sequestering cytochrome c. Biochem Biophys Res Commun Guglielmi L, Martineau P. 2009. Intrabody expression in eukaryotic cells. Methods Mol Biol 562: 195-203 Guglielmi L, Martineau P. 2009. Expression of Single-Chain Fv Fragments in E. coli Cytoplasm. Methods Mol Biol 562: 215-24 Estephan E, Saab MB, Larroque C, Martin M, Olsson F, Lourdudoss S, Gergely C. 2009. Peptides for functionalization of InP semiconductors. J Colloid Interface Sci 337: 358-63 Estephan E, Larroque C, Bec N, Martineau P, Cuisinier FJ, Cloitre T, Gergely C. 2009. Selection and mass spectrometry characterization of peptides targeting semiconductor surfaces. Biotechnol Bioeng 104: 1121-31 Vie N, Copois V, Mollevi C, Denis V, Bec N, Robert B, Fraslon C, Conseiller E, Molina F, Larroque C, Martineau P, Del Rio M, Gongora C. 2008. Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells. Mol Cancer 7: 14 Molina S, missé D, Roche S, Badiou S, Cristol JP, Bonfils C, Dierick JF, Veas F, levayer T, Bonnefont-Rousselot, Maurel p, Coste J, C F-W. 2008. Identification of apolipoprotein C-III as a potential plasmatic biomarker associated with the resolution Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
of hepatitis C virus infection. Proteomics Clin Appl 2: 751-61 Mazuc E, Villoutreix BO, Malbec O, Roumier T, Fleury S, Leonetti JP, Dombrowicz D, Daeron M, Martineau P, Dariavach P. 2008. A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally. J Allergy Clin Immunol 122: 188-94 Maurice T, Duclot F, Meunier J, Naert G, Givalois L, Meffre J, Celerier A, Jacquet C, Copois V, Mechti N, Ozato K, Gongora C. 2008. Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice. Neuropsychopharmacology 33: 1584-602 Granci V, Bibeau F, Krama A, Boissiere-Michot F, Thezenas S, Thirion A, Gongora C, Martineau P, Del Rio M, Ychou M. 2008. Prognostic significance of TRAIL-R1 and TRAIL-R3 expression in metastatic colorectal carcinomas. Eur J Cancer 44: 2312-8 Gongora C, Candeil L, Vezzio N, Copois V, Denis V, Bareil C, Molina F, Fraslon C, Conseiller E, Pau B, Martineau P, Del Rio M. 2008. Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38. Cancer Biol Ther 7 Estephan E, Larroque C, Cuisinier FJ, Balint Z, Gergely C. 2008. Tailoring GaN Semiconductor Surfaces with Biomolecules. J Phys Chem B 112: 8799-805 Didier P, Weiss E, Sibler AP, Philibert P, Martineau P, Bigot JY, Guidoni L. 2008. Femtosecond spectroscopy probes the folding quality of antibody fragments expressed as GFP fusions in the cytoplasm. Biochem Biophys Res Commun 366: 878-84 André Pèlegrin
Immunociblage et Radiobiologie en Oncologie
Rigo M, Chentouf M, Pelegrin A, Chardes T. 2011. CD4 ligation excludes the Carma1-Bcl10-MALT1 complex from GM1-positive membrane rafts in CD3/CD28 activated T cells. Cell Immunol 29: 29 Ladjemi MZ, Chardes T, Corgnac S, Garambois V, Morisseau S, Robert B, Bascoul-Mollevi C, Ait Arsa I, Jacot W, Pouget JP, Pelegrin A, Navarro-Teulon I. 2011. Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice. Breast Cancer Res 13: R17 Gaborit N, Larbouret C, Vallaghe J, Peyrusson F, Bascoul-Mollevi C, Crapez E, Azria D, Chardes T, Poul MA, Mathis G, Bazin H, Pelegrin A. 2011. Time resolved fluorescence resonance energy transfer (TR-FRET) to analyze the disruption of EGFR/HER2 dimers: a new method to evaluate the efficiency of targeted therapy using monoclonal antibodies. J Biol Chem 286: 11337-45 Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
van der Pas MH, van Dongen GA, Cailler F, Pelegrin A, Meijerink WJ. 2010. Sentinel node procedure of the sigmoid using indocyanine green: feasibility study in a goat model. Surg Endosc 24: 2182-7 Thierry AR, Mouliere F, Gongora C, Ollier J, Robert B, Ychou M, Del Rio M, Molina F. 2010. Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts. Nucleic Acids Res 38: 6159-75 Schmidt J, Garambois V, Rocheblave L, Martinez J, Pelegrin A, Cavelier F, Vives E. 2010. Cyclization of peptides through a urea bond: application to the Arg-Gly-Asp tripeptide. Chembiochem 11: 1083-92 Larbouret C, Robert B, Bascoul-Mollevi C, Penault-Llorca F, Ho-Pun-Cheung A, Morisseau S, Navarro-Teulon I, Mach JP, Pelegrin A, Azria D. 2010. Combined cetuximab and trastuzumab are superior to gemcitabine in the treatment of human pancreatic carcinoma xenografts. Ann Oncol 21: 98-103 Ladjemi MZ, Jacot W, Chardes T, Pelegrin A, Navarro-Teulon I. 2010. Anti-HER2 vaccines: new prospects for breast cancer therapy. Cancer Immunol Immunother 59: 1295-312 Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, Bibeau F, Boissiere-Michot F, Thezenas S, Cellier D, Azria D, Rouanet P, Senesse P, Ychou M, Lopez-Crapez E. 2010. A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer. Pharmacogenomics J Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, Bibeau F, Boissiere-Michot F, Cellier D, Azria D, Rouanet P, Senesse P, Ychou M, Lopez-Crapez E. 2010. EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer. Int J Cancer 128: 2938-46 Chentouf M, Rigo M, Ghannam S, Navarro-Teulon I, Mongrand S, Pelegrin A, Chardes T. 2010. The lipid-modulating effects of a CD4-specific recombinant antibody correlate with ZAP-70 segregation outside membrane rafts. Immunol Lett 133: 62-9 Boudousq V, Ricaud S, Garambois V, Bascoul-Mollevi C, Boutaleb S, Busson M, Quenet F, Colombo PE, Bardies M, Kotzki PO, Navarro-Teulon I, Pelegrin A, Pouget JP. 2010. Brief Intraperitoneal Radioimmunotherapy of Small Peritoneal Carcinomatosis Using High Activities of Noninternalizing 125I-Labeled Monoclonal Antibodies. J Nucl Med 51: 1748-55 Stork R, Campigna E, Robert B, Mueller D, Kontermann RE. 2009. Biodistribution of a bispecific single-chain diabody and its half-life extended derivatives. J Biol Chem 284: 25612-9 Santoro L, Boutaleb S, Garambois V, Bascoul-Mollevi C, Boudousq V, Kotzki PO, Pelegrin M, Navarro-Teulon I, Pelegrin A, Pouget JP. 2009. Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small- Bibliodoc
Institut de Recherche en Cancérologie de Montpellier
volume peritoneal carcinomatosis. J Nucl Med 50: 2033-41 Pelegrin A, Robert B. 2009. [Bispecific antibodies: what future?]. Med Sci (Paris) 25: 1155-8 Pelegrin A, Robert B. 2009. [Bispecific antibodies: what future?]. Med Sci (Paris) 25: 1155-8 Leroy C, Fialin C, Sirvent A, Simon V, Urbach S, Poncet J, Robert B, Jouin P, Roche S. 2009. Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells. Cancer Res 69: 2279-86 Ladjemi MZ, Jacot W, Pelegrin A, Navarro-Teulon I. 2009. [Anti-HER2 vaccines: The HER2 immunotargeting future?]. Pathol Biol (Paris) Ladjemi MZ, Jacot W, Pelegrin A, Navarro-Teulon I. 2009. [Anti-HER2 vaccines: The HER2 immunotargeting future?]. Pathol Biol (Paris) Faruque OM, Le-Nguyen D, Lajoix AD, Vives E, Petit P, Bataille D, Hani el H. 2009. Cell-permeable peptide-based disruption of endogenous PKA-AKAP complexes: a tool for studying the molecular roles of AKAP-mediated PKA subcellular anchoring. Am J Physiol Cell Physiol 296: C306-16 Boutaleb S, Pouget J, Hindorf C, Pelegrin A, Barbet J, Kotzki PO, Bardies M. 2009. Impact of mouse model on preclinical dosimetry in targeted radionuclide therapy. Proceedings of the IEEE In Press Behar G, Chames P, Teulon I, Cornillon A, Alshoukr F, Roquet F, Pugniere M, Teillaud JL, Gruaz-Guyon A, Pelegrin A, Baty D. 2009. Llama single-domain antibodies directed against nonconventional epitopes of tumor-associated carcinoembryonic antigen absent from nonspecific cross-reacting antigen. FEBS J Alvarez-Rueda N, Ladjemi MZ, Behar G, Corgnac S, Pugniere M, Roquet F, Bascoul-Mollevi C, Baty D, Pelegrin A, Navarro-Teulon I. 2009. A llama single domain anti-idiotypic antibody mimicking HER2 as a vaccine: Immunogenicity and efficacy. Vaccine 27: 4826-33 Ychou M, Azria D, Menkarios C, Faurous P, Quenet F, Saint-Aubert B, Rouanet P, Pelegrin M, Bascoul-Mollevi C, Guerreau D, Saccavini JC, Mach JP, Artus JC, Pelegrin A. 2008. Adjuvant Radioimmunotherapy Trial with Iodine-131-Labeled Anti-Carcinoembryonic Antigen Monoclonal Antibody F6 F(ab')2 after Resection of Liver Metastases from Colorectal Cancer. Clin Cancer Res 14: 3487-93 Vives E, Schmidt J, Pelegrin A. 2008. Cell-penetrating and cell-targeting peptides in drug delivery. Biochim Biophys Acta 1786: 126-38 Vives E, Schmidt J, Pelegrin A. 2008. Cell-penetrating and cell-targeting peptides in drug delivery. Biochim Biophys Acta 1786: 126-38 Bibliodoc
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Stirnemann K, Romero JF, Baldi L, Robert B, Cesson V, Besra GS, Zauderer M, Wurm F, Corradin G, Mach JP, Macdonald HR, Donda A. 2008. Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice. J Clin Invest 118: 994-1005 Pouget JP, Santoro L, Raymond L, Chouin N, Bardies M, Bascoul-Mollevi C, Huguet H, Azria D, Kotzki PO, Pelegrin M, Vives E, Pelegrin A. 2008. Cell Membrane is a More Sensitive Target than Cytoplasm to Dense Ionization Produced by Auger Electrons. Radiat Res 170: 192-200 Kucharczak J, Charrasse S, Comunale F, Zappulla J, Robert B, Teulon-Navarro I, Pelegrin A, Gauthier-Rouviere C. 2008. R-Cadherin expression inhibits myogenesis and induces myoblast transformation via Rac1 GTPase. Cancer Res 68: 6559-68 Germain C, Campigna E, Salhi I, Morisseau S, Navarro-Teulon I, Mach JP, Pelegrin A, Robert B. 2008. Redirecting NK cells mediated tumor cell lysis by a new recombinant bifunctional protein. Protein Eng Des Sel 21: 665-72 Azria D, Ozsahin M, Kramar A, Peters S, Atencio DP, Crompton NE, Mornex F, Pelegrin A, Dubois JB, Mirimanoff RO, Rosenstein BS. 2008. Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy. Clin Cancer Res 14: 6284-8 Charles Theillet
Identité et Plasticité Tumorale
Le Bechec A, Portales-Casamar E, Vettter G, Moes M, Zindy PJ, Saumet A, Arenillas D, Theillet C, Wasserman WW, Lecellier CH, Friederich E. 2011. MIR@NT@N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in meta-regulation network model. BMC Bioinformatics 12: 67 Fabregue M, Bringay S, Poncelet P, Teisseire M, Orsetti B. 2011. Mining microarray data to predict the histological grade of a breast cancer. J Biomed Inform 21: 21 Chambon M, Orsetti B, Berthe ML, Bascoul-Mollevi C, Rodriguez C, Duong V, Gleizes M, Thenot S, Bibeau F, Theillet C, Cavailles V. 2011. Prognostic Significance of TRIM24/TIF-1alpha Gene Expression in Breast Cancer. Am J Pathol 178: 1461-9 Vetter G, Saumet A, Moes M, Vallar L, Le Bechec A, Laurini C, Sabbah M, Arar K, Theillet C, Lecellier CH, Friederich E. 2010. miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers. Oncogene 29: 4436-48 Tuduri S, Crabbe L, Tourriere H, Coquelle A, Pasero P. 2010. Does interference between replication and transcription contribute to genomic instability in cancer cells? Cell Cycle 9: 1886-92 Tuduri S, Crabbe L, Tourriere H, Coquelle A, Pasero P. 2010. Does interference Bibliodoc
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between replication and transcription contribute to genomic instability in cancer cells? Cell Cycle 9: 1886-92 Theillet C. 2010. What do we learn from HER2-positive breast cancer genomic profiles? Breast Cancer Res 12: 107 Docquier A, Harmand PO, Fritsch S, Chanrion M, Darbon JM, Cavailles V. 2010. The transcriptional coregulator RIP140 represses E2F1 activity and discriminates breast cancer subtypes. Clin Cancer Res 16: 2959-70 de Herreros AG, Peiro S, Nassour M, Savagner P. 2010. Snail Family Regulation and Epithelial Mesenchymal Transitions in Breast Cancer Progression. J Mammary Gland Biol Neoplasia 15: 135-47 Tuduri S, Crabbe L, Conti C, Tourriere H, Holtgreve-Grez H, Jauch A, Pantesco V, De Vos J, Thomas A, Theillet C, Pommier Y, Tazi J, Coquelle A, Pasero P. 2009. Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat Cell Biol 11: 1315-24 Tuduri S, Crabbe L, Conti C, Tourriere H, Holtgreve-Grez H, Jauch A, Pantesco V, De Vos J, Thomas A, Theillet C, Pommier Y, Tazi J, Coquelle A, Pasero P. 2009. Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat Cell Biol 11: 1315-24 Pencreach E, Guerin E, Nicolet C, Lelong-Rebel I, Voegeli AC, Oudet P, Larsen AK, Gaub MP, Guenot D. 2009. Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis. Clin Cancer Res 15: 1297-307 Nicolet C, Guerin E, Neuville A, Kerckaert JP, Wicker N, Bergmann E, Brigand C, Kedinger M, Gaub MP, Guenot D. 2009. Evidence for various 20q status using allelotyping, CGH arrays, and quantitative PCR in distal CIN colon cancers. Cancer Lett 282: 195-204 Klymkowsky MW, Savagner P. 2009. Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe. Am J Pathol 174: 1588-93 Wolthuis R, Travo A, Nicolet C, Neuville A, Gaub MP, Guenot D, Ly E, Manfait M, Jeannesson P, Piot O. 2008. IR spectral imaging for histopathological characterization of xenografted human colon carcinomas. Anal Chem 80: 8461-9 Chanrion M, Negre V, Fontaine H, Salvetat N, Bibeau F, Mac Grogan G, Mauriac L, Katsaros D, Molina F, Theillet C, Darbon JM. 2008. A gene expression signature that can predict the recurrence of tamoxifen-treated primary breast cancer. Clin Cancer Res 14: 1744-52 Chanrion M, Darbon JM. 2008. [Gene expression profiling of ER+ breast cancers: to discriminate the poor prognosis tumors or to define the most suitable treatment?]. Bull Cancer 95: 513-8 Bibliodoc
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Bertucci F, Orsetti B, Negre V, Finetti P, Rouge C, Ahomadegbe JC, Bibeau F, Mathieu MC, Treilleux I, Jacquemier J, Ursule L, Martinec A, Wang Q, Benard J, Puisieux A, Birnbaum D, Theillet C. 2008. Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles. Oncogene 27: 5359-72 Arnoux V, Nassour M, L'Helgoualc'h A, Hipskind RA, Savagner P. 2008. Erk5 Controls Slug Expression and Keratinocyte Activation during Wound Healing. Mol Biol Cell 19: 4738-49 Bibliodoc
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