Material Safety Data Sheet Ethyl acetate 1 Chemical product and company identification Common name : Ethyl acetate Code : 7872 Supplier : Sasol Solvents MSDS# : SOLV0000160. Trading as Sasol Chemicals North America LLC,900 Threadneedle, Suite 100Houston, Texas 77079 USATelephone: 281 588 3000Facsimile: 281 588 3381Synonym : Acetidin, Acetic Acid Ethyl Ester, Ethyl Acetic Validation date : 09/05/2002. Trade name : Ethyl acetate. Print date : 09/05/2002. Material uses : Coatings: Solvent. Responsible name : Lehlohonolo B Mothebe Industrial applications: Organic syntheses. Solvent. Polyurethane systems. Pharmaceutical industry: Pharmaceuticals.Manufacturer : Sasol Chemical Industries Ltd. In case of emergency : Chemtrec: 800-424-9300 Republic of South AfricaTEL: +27 11 871-81112 Composition / information on ingredients Name CAS # % by weight Exposure limits ACGIH (United States, 2002). TWA: 400 ppm TWA: 1440 mg/m3 OSHA (United States, 2002). TWA: 400 ppm TWA: 1400 mg/m3 3 Hazards identification Physical state and appearance : Liquid. (Clear colorless liquid.) Emergency overview : WARNING! HIGHLY FLAMMABLE LIQUID AND VAPOR, VAPOR MAY CAUSE FLASH FIRE. MAY CAUSE EYE IRRITATION.Keep away from heat, sparks and flame. Avoid contact with eyes, skin and clothing. Avoid prolongedcontact with eyes, skin, and clothing. Avoid breathing vapor or mist. Keep container closed. Use onlywith adequate ventilation. Wash thoroughly after handling.Routes of entry : Absorbed through skin. Eye contact. Inhalation. Ingestion. Potential acute health effects Eyes : Hazardous in case of eye contact (irritant). Skin : Hazardous in case of skin contact. Skin inflammation is characterized by itching, scaling, reddening, Inhalation : Hazardous in case of inhalation. Continued on Next Page Ethyl acetate Page: 2/6 Ingestion : Hazardous in case of ingestion. Potential chronic health : CARCINOGENIC EFFECTS: Classified A5 (Not suspected for human.) by ACGIH. effects MUTAGENIC EFFECTS: Not listed. TERATOGENIC EFFECTS: Not listed. Medical conditions : Persons with pre-existing chronic lung, skin, blood, liver or kidney diseases might be at increased risk aggravated by overexposure: Persons undergoing ANTABUSE treatment might experience violent gastrointestinal distress, flushingor hypotension. Tobacco smoking increases the risk of lung disease in workers exposed to ethylacetate. Persons simultaneously exposed to ethanol or acetaldehyde might be more sensitive.Overexposure : Ethyl acetate is a primary irritant. It can affect you if breathed in or by passing through the skin. /signs/symptoms Inhalation exposure can cause irritation of eye, nose, throat and upper respiratory tract. It canproduce mild Central Nervous System depression, with symptoms such as lightheadedness, dizzinessand to pass out. Repeated contact can cause cracking of the skin.See toxicological information (section 11) 4 First aid measures Eye contact : Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.Skin contact : In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Cold water may be used.Wash clothing beforereuse. Thoroughly clean shoes before reuse. Get medical attention.Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give Ingestion : Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Getimmediate medical attention.Notes to physician : Support respiratory and cardiovascular function. 5 Fire fighting measures Flammability of the product : Flammable. Autoignition temperature : 427°C (800.6°F) Flash points : CLOSED CUP: -4.4°C (24.1°F). OPEN CUP: 4°C (39.2°F). (Cleveland). Flammable limits : LOWER: 2.2% UPPER: 11.5% Products of combustion : These products are carbon oxides (CO, CO2). Fire hazards in presence of : Highly flammable in presence of open flames and sparks, of heat, of moisture. various substances Explosion hazards in presence : Risks of explosion of the product in presence of mechanical impact: Not available. of various substances Risks of explosion of the product in presence of static discharge: Possible. Vapors may form explosive mixtures with air. Poses a moderate explosion hazard when exposed toflame. Ethyl acetate froms potentially explosive reactions with lithium tetrahydroaluminate. Ignites oncontact with tert-butoxide. Forms a violent reaction with chlorosulfonic acid and oleum.Fire fighting media : SMALL FIRE: Use DRY chemical powder. and instructions LARGE FIRE: Use alcohol foam, water spray or fog. Cool containing vessels with water jet in order toprevent pressure build-up, autoignition or explosion.Protective clothing (fire) : Wear MSHA/NIOSH approved self-contained breathing apparatus or equivalent and full protective Special remarks on fire hazards : Vapor may travel considerable distance to source of ignition and flash back. When heated to decomposition it emits acrid smoke and irritating fumes. Cool containers with flooding quantities ofwater until well after fire is out.Special remarks on explosion : Vapor explosion hazard indoors, outdoors or in sewers. Containers may explode when heated. hazards Vapors may form explosive mixtures with air. Most vapors are heavier than air, they will spread alongthe grown and collect in low or confined areas (sewers, basements, tanks).Continued on Next Page Ethyl acetate Page: 3/6 6 Accidental release measures Small spill and leak : Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate Large spill and leak : Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Do not touch spilled material. Prevent entryinto sewers, basements or confined areas; dike if needed.7 Handling and storage Handling : Keep away from heat, sparks and flame. Keep container closed. Use only with adequate ventilation. To avoid fire or explosion, dissipate static electricity during transfer by grounding and bondingcontainers and equipment before transferring material. Use explosion-proof electrical (ventilating,lighting and material handling) equipment.Storage : Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid all possible sources of ignition (spark orflame).8 Exposure controls, personal protection Engineering controls : Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective threshold limit value. Ensure that eyewash stations and safety showersare proximal to the work-station location.Personal protection Eyes : Splash goggles. Body : Chemical resistant protective suit. Respiratory : Vapor respirator. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Wear appropriate respirator when ventilation is inadequate.Hands : Butyl rubber gloves. Feet : Chemical resistant safety boots. Protective clothing (pictograms) : Personal protection in case of a : Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult alarge spill specialist BEFORE handling this product.Product name Exposure limits ACGIH (United States, 2002). TWA: 400 ppm TWA: 1440 mg/m3 OSHA (United States, 2002). TWA: 400 ppm TWA: 1400 mg/m3 9 Physical and chemical properties Physical state and appearance : Liquid. (Clear colorless liquid.) Color : Clear, colorless liquid with a fruity odor. Odor : Ether-like, fragrance, fruity, pineapple-like odour. Taste : Pleasant, bitter-sweet, wine-like burning taste. Molecular weight : 88.12g/mole Molecular formula : C4-H8-O2 pH (1% soln/water) : 7 [Neutral.] Boiling/condensation point : 77°C (170.6°F) Melting/freezing point : -83.6°C (-118.5°F) Critical temperature : 250°C (482°F) Continued on Next Page Ethyl acetate Page: 4/6 Specific gravity : 0.902 (Water = 1) Vapor pressure : 76 mm of Hg (@ 20°C) Vapor density : 3.04 (Air = 1) Volatility : 100% (v/v). Odor threshold : 18 ppm Evaporation rate : 6.2 [Solvent] VOC : Not available. Viscosity : 0.44 cP LogKow : The product is more soluble in oil; log(oil/water) = 0.7 Ionicity (in water) : Not available. Dispersion properties : See solubility in water, methanol, diethyl ether. Solubility : Soluble in cold water, methanol, diethyl ether. Physical chemical comments : No additional remark. 10 Stability and reactivity Stability and reactivity : The product is stable. Conditions of instability : Overheating, flames, sources of ignition or direct sunlight. Must not come in contact with oxidising agents, perchlorates, peroxides, chromic and nitric acids.Incompatibility with various : Reactive with oxidizing agents, acids, alkalis, moisture. substances Hazardous decomposition : When heated ethyl acetate emits acrid smoke and irritating fumes. products Hazardous polymerization : Will not occur. 11 Toxicological information Toxicity to Animals : Acute oral toxicity (LD50): 5620 mg/kg [Rat]. Acute toxicity of the vapor (LC50): 19596 ppm 4 hour(s) [Rat.].Chronic effects on humans : CARCINOGENIC EFFECTS: Classified A5 (Not suspected for human.) by ACGIH. Other toxic effects on humans : Hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of inhalation. Slightly hazardous in case of ingestion.Special remarks on toxicity to : No additional remark. animals Special remarks on chronic : No additional remark. effects on humans Special remarks on other toxic : Exposure can cause nausea, headache and vomiting. Material is irritating to mucous membranes and effects on humans 12 Ecological information Ecotoxicity : LC50: 1540 ppm/24 hrs [Brine shrimp]. BOD and COD : 36-68 % in 5 days. Biodegradable/OECD : Biodegradable. Mobility : No data available. Products of degradation : Will NOT bioaccumulate. Toxicity of the products of : The products of biodegradation are less toxic than the original product. biodegradation Special remarks on the products : No additional remark. of biodegradation Continued on Next Page Ethyl acetate Page: 5/6 13 Disposal considerations Waste information : Waste must be disposed of in accordance with federal, state and local environmental control Waste stream : RCRA Hazardous Waste: D001, RQ of 5000 lbs. Consult your local or regional authorities. 14 Transport information Regulatory UN Proper shipping name Class Packing Label Additional information number group information DOT Reportable Classification Quantity 5000 lbs. (2268 kg) TDG Classification IMDG Class IATA-DGR Class 15 Regulatory information HCS classification : HCS CLASS: Flammable liquid having a flash point lower than 37.8°C (100°F). U.S. Federal regulations : TSCA 5(e) substance consent order: Ethyl acetate TSCA 8(a) IUR: Ethyl acetateTSCA 8(b) inventory: Ethyl acetateTSCA 12(b) one time export: Ethyl acetateSARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products werefound.SARA 313 toxic chemical notification and release reporting: No products were found.Clean Water Act (CWA) 307: No products were found.Clean Water Act (CWA) 311: No products were found.Clean air act (CAA) 112 accidental release prevention: No products were found.Clean air act (CAA) 112 regulated flammable substances: No products were found.Clean air act (CAA) 112 regulated toxic substances: No products were found.State regulations : Rhode Island RTK hazardous substances: Ethyl acetate Pennsylvania RTK: Ethyl acetate: (environmental hazard)Florida: Ethyl acetateMinnesota: Ethyl acetateMassachusetts RTK: Ethyl acetateNew Jersey: Ethyl acetateNew Jersey spill list: Ethyl acetateCalifornia prop. 65: No products were found.EU Regulations Continued on Next Page Ethyl acetate Page: 6/6 Hazard symbol(s) : Classification : Highly flammable, Irritant Risk phrases : R11- Highly flammable. R36- Irritating to eyes. R66- Repeated exposure may cause skin dryness or cracking. R67- Vapors may cause drowsiness and dizziness.Safety phrases : S16- Keep away from sources of ignition - No smoking. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33- Take precautionary measures against static discharges.EINECS Number : 205-500-4. 16 Other information National Fire Protection Association 3 Fire Hazard (U.S.A.) Health 1 0 Reactivity Specific hazard References : - LOLI Database: The regulated Chemicals List of Lists.
- CHEMINFO: Canadian Centre for Occupational Health and Safety, Issue: 97-3 (August, 1997).-BDH; Hazard Data Disk, Version 3.- CESARS: Chemical Evaluation and Retrieval System, Producedby: Ontario Ministry of Environment and Michigan Department of Natural Resouces, Issue:97-3(August, 1997).- TOMES Plus System: Toxicology, Occupational Medicine & Environmental Series:incorporating:- MEDITEX, HAZARDTEXT, 1st Medical Response Protocols, INFOTEXT, HSDB, CHRIS,OHM/TADS, IRIS, NIOSH Pocket Guide, RTECS, NJ Fact Sheets, North American EmergencyResponse Guides, REPROTEXT, REPROTOX, TERIS, Shepard's Catalog of Teratogenic Agents. Other special considerations : No additional remark. Date of printing : 09/05/2002. Date of issue : 09/05/2002. Date of previous issue : No Previous Validation. Version : 1 Notice to reader This MSDS summarises at the date of issue our best knowledge of the health, safety and environmental hazard information related to the product, and in particular how to safely handle, use, store and transport the product in the workplace. Since SASOL and its subsidiaries cannot anticipate or control the conditions under which the product may be handled, used, stored or transported, each user must, prior to usage, review this MSDS in the context of how the user intends to handle, use, store or transport the product in the workplace and beyond, and communicate such information to all relevant parties.If clarification or further information is needed to ensure that an appropriate assessment can be made, the user should contact this company. We shall not assume any liability for the accuracy or completeness of the information contained herein or any advice given unless there has been gross negligence onour part. In such event our liability shall be limited only to direct damages suffered. Our responsibility for product as sold is subject to our standard terms andconditions, a copy of which is sent to our customers and is also available upon request. All risk associated with the possession and application of the product passes ondelivery.
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